功能： domain:The N-terminus of the RabBD domain is necessary and sufficient for interaction with RAB27A.,function:Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells.,similarity:Contains 1 FYVE-type zinc finger.,similarity:Contains 1 RabBD (Rab-binding) domain.,subcellular location:Recruited to the vesicle membrane in a GTP-and RAB3B-dependent manner in epithelial cells.,subunit:Recruited to dense-core vesicles through specific interaction with RAB27A in endocrine cells. Interacts with RAB3A, RAB3B, RAB3C and RAB3D. Interacts with ZYX.,tissue specificity:Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Cytoplasmic vesicle, secretory vesicle membrane . Recruited to the vesicle membrane in a GTP- and RAB3B-dependent manner in epithelial cells.
组织表达： Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells.
功能： domain:The N-terminus of the RabBD domain is necessary and sufficient for interaction with RAB27A.,function:Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells.,similarity:Contains 1 FYVE-type zinc finger.,similarity:Contains 1 RabBD (Rab-binding) domain.,subcellular location:Recruited to the vesicle membrane in a GTP-and RAB3B-dependent manner in epithelial cells.,subunit:Recruited to dense-core vesicles through specific interaction with RAB27A in endocrine cells. Interacts with RAB3A, RAB3B, RAB3C and RAB3D. Interacts with ZYX.,tissue specificity:Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Cytoplasmic vesicle, secretory vesicle membrane . Recruited to the vesicle membrane in a GTP- and RAB3B-dependent manner in epithelial cells.
组织表达： Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells.
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