MBD2 rabbit pAb

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MBD2 rabbit pAb

商品货号： PLA020259

适应性： 人,小鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： MBD2
蛋白名称： MBD2
Human_gene_id： 8932
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8932
Human_swiss_prot_no： Q9UBB5
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9UBB5/entry
Mouse_gene_id： 17191
Mouse_gene_link： https://www.uniprot.org/uniprot/17191
Mouse_swiss_prot_no： Q9Z2E1
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q9Z2E1
特异性： This antibody detects endogenous levels of MBD2 at Human/Mouse
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
分子量： 45kD
功能： function:Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemi-methylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Isoform 1 may enhance the activation of some unmethylated cAMP-responsive promoters. Reports about DNA demethylase activity of isoform 2 are contradictory.,similarity:Contains 1 MBD (methyl-CpG-binding) domain.,subcellular location:Nuclear, in discrete foci. Detected at replication foci in late S phase.,subunit:Heterodimer with MBD3. Part of the MeCP1 complex that contains HDAC1 and HDAC2. Binds DNMT1, MIZF, XAB1, SIN3A, p66-alpha and p66-beta. Isoform 1 binds DHX9, but isoform 2 does not.,tissue specificity:Highly expressed in brain, heart, kidney, stomach, testis and placenta.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Nuclear, in discrete foci. Detected at replication foci in late S phase.
组织表达： Highly expressed in brain, heart, kidney, stomach, testis and placenta.
科研货号： PLA020259

MBD2 rabbit pAb

Catalog No PLA020259

Product information

基因名称： MBD2
蛋白名称： MBD2
Human_gene_id： 8932
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8932
Human_swiss_prot_no： Q9UBB5
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9UBB5/entry
Mouse_gene_id： 17191
Mouse_gene_link： https://www.uniprot.org/uniprot/17191
Mouse_swiss_prot_no： Q9Z2E1
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q9Z2E1
特异性： This antibody detects endogenous levels of MBD2 at Human/Mouse
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
分子量： 45kD
功能： function:Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemi-methylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Isoform 1 may enhance the activation of some unmethylated cAMP-responsive promoters. Reports about DNA demethylase activity of isoform 2 are contradictory.,similarity:Contains 1 MBD (methyl-CpG-binding) domain.,subcellular location:Nuclear, in discrete foci. Detected at replication foci in late S phase.,subunit:Heterodimer with MBD3. Part of the MeCP1 complex that contains HDAC1 and HDAC2. Binds DNMT1, MIZF, XAB1, SIN3A, p66-alpha and p66-beta. Isoform 1 binds DHX9, but isoform 2 does not.,tissue specificity:Highly expressed in brain, heart, kidney, stomach, testis and placenta.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Nuclear, in discrete foci. Detected at replication foci in late S phase.
组织表达： Highly expressed in brain, heart, kidney, stomach, testis and placenta.
科研货号： PLA020259

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