功能： disease:Defects in DAZL may be a cause of infertility due to severe oligozoospermia (AZ) and non obstructive azoospermia.,domain:The DAZ-like domain mediates the interaction with DAZAP1 and DAZAP2.,function:RNA-binding protein, which is essential for gametogenesis. Plays a central role during spermatogenesis. May act by binding to the 3'-UTR of mRNA and thereby regulating the translation of key transcripts.,similarity:Belongs to the RRM DAZ family.,similarity:Contains 1 DAZ-like domain.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subcellular location:Predominantly cytoplasmic (By similarity). Nuclear in spermatogonia until near the end of the meiotic prophase and cytoplasmic localization from then onward.,subunit:Homodimer and heterodimer (By similarity). Forms a heterodimer with DAZ. Interacts with BOLL, DAZAP1 and DAZAP2. Interacts with PUM2.,tissue specificity:Testis specific.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Nucleus . Predominantly cytoplasmic. Nuclear in spermatogonia until near the end of the meiotic prophase and cytoplasmic localization from then onward. .
功能： disease:Defects in DAZL may be a cause of infertility due to severe oligozoospermia (AZ) and non obstructive azoospermia.,domain:The DAZ-like domain mediates the interaction with DAZAP1 and DAZAP2.,function:RNA-binding protein, which is essential for gametogenesis. Plays a central role during spermatogenesis. May act by binding to the 3'-UTR of mRNA and thereby regulating the translation of key transcripts.,similarity:Belongs to the RRM DAZ family.,similarity:Contains 1 DAZ-like domain.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subcellular location:Predominantly cytoplasmic (By similarity). Nuclear in spermatogonia until near the end of the meiotic prophase and cytoplasmic localization from then onward.,subunit:Homodimer and heterodimer (By similarity). Forms a heterodimer with DAZ. Interacts with BOLL, DAZAP1 and DAZAP2. Interacts with PUM2.,tissue specificity:Testis specific.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Nucleus . Predominantly cytoplasmic. Nuclear in spermatogonia until near the end of the meiotic prophase and cytoplasmic localization from then onward. .
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