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FKBP1B Polyclonal Antibody
商品货号: PLA019784
适 应 性: 人,大鼠,小鼠,
IHC ELISA
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: FKBP1B FKBP12.6 FKBP1L FKBP9 OTK4
  • 蛋白名称: FKBP1B
  • Human_gene_id: 2281
  • Human_swiss_prot_no: P68106
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/P68106/entry
  • 特异性: This antibody detects endogenous levels of human FKBP1B
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: IHC-p 1:50-200, ELISA(peptide)1:5000-20000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B;EC 5.2.1.8;12.6 kDa FK506-binding protein;12.6 kDa FKBP;FKBP-12.6;FK506-binding protein 1B;FKBP-1B;Immunophilin FKBP12.6;Rotamase;h-FKBP-12)
  • 功能: catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,enzyme regulation:Inhibited by both FK506 and rapamycin.,function:Associates with the ryanodine receptor (RYR-2) in cardiac muscle sarcoplasmic reticulum and may play a unique physiological role in excitation-contraction coupling in cardiac muscle. There are four molecules of FKBP12.6 per heart muscle RYR. Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,similarity:Belongs to the FKBP-type PPIase family. FKBP1 subfamily.,similarity:Contains 1 PPIase FKBP-type domain.,tissue specificity:Ubiquitous for both isoforms with highest levels in brain and thymus.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Sarcoplasmic reticulum .
  • 组织表达: Detected in heart muscle (at protein level). Isoform 1 and isoform 2 are ubiquitous with highest levels in brain and thymus.
  • 科研货号: PLA019784
FKBP1B Polyclonal Antibody
Catalog No PLA019784
Product information
  • 基因名称: FKBP1B FKBP12.6 FKBP1L FKBP9 OTK4
  • 蛋白名称: FKBP1B
  • Human_gene_id: 2281
  • Human_swiss_prot_no: P68106
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/P68106/entry
  • 特异性: This antibody detects endogenous levels of human FKBP1B
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: IHC-p 1:50-200, ELISA(peptide)1:5000-20000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B;EC 5.2.1.8;12.6 kDa FK506-binding protein;12.6 kDa FKBP;FKBP-12.6;FK506-binding protein 1B;FKBP-1B;Immunophilin FKBP12.6;Rotamase;h-FKBP-12)
  • 功能: catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,enzyme regulation:Inhibited by both FK506 and rapamycin.,function:Associates with the ryanodine receptor (RYR-2) in cardiac muscle sarcoplasmic reticulum and may play a unique physiological role in excitation-contraction coupling in cardiac muscle. There are four molecules of FKBP12.6 per heart muscle RYR. Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,similarity:Belongs to the FKBP-type PPIase family. FKBP1 subfamily.,similarity:Contains 1 PPIase FKBP-type domain.,tissue specificity:Ubiquitous for both isoforms with highest levels in brain and thymus.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Sarcoplasmic reticulum .
  • 组织表达: Detected in heart muscle (at protein level). Isoform 1 and isoform 2 are ubiquitous with highest levels in brain and thymus.
  • 科研货号: PLA019784
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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