功能： telomere maintenance, DNA metabolic process, DNA replication, RNA-dependent DNA replication, anti-apoptosis,telomere maintenance via telomerase, aging, senescence, telomere maintenance via telomere lengthening, regulation of cell death, DNA strand elongation, telomere organization, telomere assembly, telomere formation via telomerase,homeostatic process, regulation of apoptosis, negative regulation of apoptosis, regulation of programmed cell death,negative regulation of programmed cell death, chromosome organization, anatomical structure homeostasis, negative regulation of cell death,
细胞定位： Nucleus, nucleolus . Nucleus, nucleoplasm. Nucleus. Chromosome, telomere. Cytoplasm. Nucleus, PML body. Shuttling between nuclear and cytoplasm depends on cell cycle, phosphorylation states, transformation and DNA damage. Diffuse localization in the nucleoplasm. Enriched in nucleoli of certain cell types. Translocated to the cytoplasm via nuclear pores in a CRM1/RAN-dependent manner involving oxidative stress-mediated phosphorylation at Tyr-707. Dephosphorylation at this site by SHP2 retains TERT in the nucleus. Translocated to the nucleus by phosphorylation by AKT.
组织表达： Expressed at a high level in thymocyte subpopulations, at an intermediate level in tonsil T-lymphocytes, and at a low to undetectable level in peripheral blood T-lymphocytes.
科研货号： PLA002096
Total Telomerase Cell-Based Colorimetric ELISA Kit
功能： telomere maintenance, DNA metabolic process, DNA replication, RNA-dependent DNA replication, anti-apoptosis,telomere maintenance via telomerase, aging, senescence, telomere maintenance via telomere lengthening, regulation of cell death, DNA strand elongation, telomere organization, telomere assembly, telomere formation via telomerase,homeostatic process, regulation of apoptosis, negative regulation of apoptosis, regulation of programmed cell death,negative regulation of programmed cell death, chromosome organization, anatomical structure homeostasis, negative regulation of cell death,
细胞定位： Nucleus, nucleolus . Nucleus, nucleoplasm. Nucleus. Chromosome, telomere. Cytoplasm. Nucleus, PML body. Shuttling between nuclear and cytoplasm depends on cell cycle, phosphorylation states, transformation and DNA damage. Diffuse localization in the nucleoplasm. Enriched in nucleoli of certain cell types. Translocated to the cytoplasm via nuclear pores in a CRM1/RAN-dependent manner involving oxidative stress-mediated phosphorylation at Tyr-707. Dephosphorylation at this site by SHP2 retains TERT in the nucleus. Translocated to the nucleus by phosphorylation by AKT.
组织表达： Expressed at a high level in thymocyte subpopulations, at an intermediate level in tonsil T-lymphocytes, and at a low to undetectable level in peripheral blood T-lymphocytes.
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