功能： M phase of mitotic cell cycle, microtubule cytoskeleton organization, mitotic cell cycle, M phase, nuclear division, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cytoskeleton organization,microtubule-based process, cell cycle, spindle organization, mitosis, intracellular signaling cascade, response to endogenous stimulus, response to hormone stimulus, response to organic substance, posttranscriptional regulation of gene expression, phosphorylation, second-messenger-mediated signaling, cell cycle process, cell cycle phase,regulation of protein stability, response to estradiol stimulus, response to estrogen stimulus, phosphoinositide-mediated signaling, organelle fission, response to steroid hormone stimulus,
相关产品： YT0326,YT0325,YP1014,YP0645,KA4005C,KA1269C
细胞定位： Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cell projection, neuron projection . Detected at the neurite hillock in developing neurons (By similarity). Localizes at the centrosome in mitotic cells from early prophase until telophase, but also localizes to the spindle pole MTs from prophase to anaphase (PubMed:9606188, PubMed:17229885, PubMed:21225229). Colocalized with SIRT2 at centrosome (PubMed:22014574). Moves to the midbody during both telophase and cytokinesis (PubMed:17726514). Associates with both the pericentriolar material (PCM) and centrioles (PubMed:22014574). The localization to the spindle poles is regulated by AAAS (PubMed:26246606). .
组织表达： Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.
功能： M phase of mitotic cell cycle, microtubule cytoskeleton organization, mitotic cell cycle, M phase, nuclear division, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cytoskeleton organization,microtubule-based process, cell cycle, spindle organization, mitosis, intracellular signaling cascade, response to endogenous stimulus, response to hormone stimulus, response to organic substance, posttranscriptional regulation of gene expression, phosphorylation, second-messenger-mediated signaling, cell cycle process, cell cycle phase,regulation of protein stability, response to estradiol stimulus, response to estrogen stimulus, phosphoinositide-mediated signaling, organelle fission, response to steroid hormone stimulus,
相关产品： YT0326,YT0325,YP1014,YP0645,KA4005C,KA1269C
细胞定位： Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cell projection, neuron projection . Detected at the neurite hillock in developing neurons (By similarity). Localizes at the centrosome in mitotic cells from early prophase until telophase, but also localizes to the spindle pole MTs from prophase to anaphase (PubMed:9606188, PubMed:17229885, PubMed:21225229). Colocalized with SIRT2 at centrosome (PubMed:22014574). Moves to the midbody during both telophase and cytokinesis (PubMed:17726514). Associates with both the pericentriolar material (PCM) and centrioles (PubMed:22014574). The localization to the spindle poles is regulated by AAAS (PubMed:26246606). .
组织表达： Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.
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