其他名称: Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain]
功能: protein import into nucleus, translocation, cell activation, regulation of protein amino acid phosphorylation, positive regulation of protein amino acid phosphorylation, acute inflammatory response, protein amino acid phosphorylation,proteolysis, protein targeting, protein import into nucleus, phosphorus metabolic process, phosphate metabolic process, ion transport, cation transport, calcium ion transport, cellular ion homeostasis, cellular calcium ion homeostasis, cellular metal ion homeostasis, intracellular protein transport, nucleocytoplasmic transport, apoptosis,activation of caspase activity, defense response, acute-phase response, inflammatory response, cell surface receptor linked signal transduction, elevation of cytosolic calcium ion concentration, intracellular signaling cascade, protein kinase cascade, JAK-STAT cascade, tyrosine phosphorylation of STAT protein, STAT protein nuclear translocation, blood coagulation, hemostasis, protein localization, cell death, response to wounding, positive regulation of biosynthetic process, regulation of calcium ion transport into cytosol, positive regulation of calcium ion transport into cytosol,positive regulation of macromolecule biosynthetic process, positive regulation of phosphorus metabolic process,positive regulation of macromolecule metabolic process, regulation of collagen metabolic process, positive regulation of collagen metabolic process, regulation of cell death, positive regulation of peptidase activity, regulation of metal ion transport, programmed cell death, protein transport, di-, tri-valent inorganic cation transport, death, phosphorylation,protein import, peptidyl-tyrosine phosphorylation, peptidyl-tyrosine modification, regulation of phosphate metabolic process, cellular homeostasis, metal ion transport, cellular cation homeostasis, cellular di-, tri-valent inorganic cation homeostasis, platelet activation, regulation of blood coagulation, positive regulation of blood coagulation, negative regulation of blood coagulation, regulation of protein modification process, positive regulation of protein modification process, regulation of response to external stimulus, regulation of cellular protein metabolic process, positive regulation of cellular protein metabolic process, regulation of homeostatic process, positive regulation of homeostatic process, regulation of collagen biosynthetic process, positive regulation of collagen biosynthetic process, protein localization in organelle, protein localization in nucleus, cellular protein localization, wound healing, regulation of phosphorylation, positive regulation of phosphorylation, homeostatic process, fibrinolysis, regulation of apoptosis,regulation of programmed cell death, positive regulation of catalytic activity, regulation of ion transport, positive regulation of ion transport, positive regulation of caspase activity, regulation of caspase activity, positive regulation of molecular function, regulation of multicellular organismal metabolic process, positive regulation of multicellular organismal metabolic process, establishment of protein localization, positive regulation of phosphate metabolic process, intracellular transport, chemical homeostasis, ion homeostasis, coagulation, regulation of coagulation,negative regulation of coagulation, positive regulation of coagulation, regulation of body fluid levels, positive regulation of transport, nuclear transport, nuclear import, regulation of phosphorus metabolic process, release of sequestered calcium ion into cytosol, positive regulation of multicellular organismal process, negative regulation of multicellular organismal process, positive regulation of protein metabolic process, regulation of release of sequestered calcium ion into cytosol, positive regulation of release of sequestered calcium ion into cytosol, regulation of sequestering of calcium ion, negative regulation of sequestering of calcium ion, regulation of hydrolase activity,positive regulation of hydrolase activity, cytosolic calcium ion homeostasis, regulation of calcium ion transport, positive regulation of calcium ion transport, regulation of peptidase activity, regulation of endopeptidase activity, metal ion homeostasis, di-, tri-valent inorganic cation homeostasis, calcium ion homeostasis, cation homeostasis, cellular chemical homeostasis, cytosolic calcium ion transport, calcium ion transport into cytosol, cellular macromolecule localization,
相关产品: YT5126,YT3862,YC0077,KA3977C,KA3520C
细胞定位: Secreted, extracellular space.
组织表达: Expressed by the liver and secreted in plasma.
其他名称: Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain]
功能: protein import into nucleus, translocation, cell activation, regulation of protein amino acid phosphorylation, positive regulation of protein amino acid phosphorylation, acute inflammatory response, protein amino acid phosphorylation,proteolysis, protein targeting, protein import into nucleus, phosphorus metabolic process, phosphate metabolic process, ion transport, cation transport, calcium ion transport, cellular ion homeostasis, cellular calcium ion homeostasis, cellular metal ion homeostasis, intracellular protein transport, nucleocytoplasmic transport, apoptosis,activation of caspase activity, defense response, acute-phase response, inflammatory response, cell surface receptor linked signal transduction, elevation of cytosolic calcium ion concentration, intracellular signaling cascade, protein kinase cascade, JAK-STAT cascade, tyrosine phosphorylation of STAT protein, STAT protein nuclear translocation, blood coagulation, hemostasis, protein localization, cell death, response to wounding, positive regulation of biosynthetic process, regulation of calcium ion transport into cytosol, positive regulation of calcium ion transport into cytosol,positive regulation of macromolecule biosynthetic process, positive regulation of phosphorus metabolic process,positive regulation of macromolecule metabolic process, regulation of collagen metabolic process, positive regulation of collagen metabolic process, regulation of cell death, positive regulation of peptidase activity, regulation of metal ion transport, programmed cell death, protein transport, di-, tri-valent inorganic cation transport, death, phosphorylation,protein import, peptidyl-tyrosine phosphorylation, peptidyl-tyrosine modification, regulation of phosphate metabolic process, cellular homeostasis, metal ion transport, cellular cation homeostasis, cellular di-, tri-valent inorganic cation homeostasis, platelet activation, regulation of blood coagulation, positive regulation of blood coagulation, negative regulation of blood coagulation, regulation of protein modification process, positive regulation of protein modification process, regulation of response to external stimulus, regulation of cellular protein metabolic process, positive regulation of cellular protein metabolic process, regulation of homeostatic process, positive regulation of homeostatic process, regulation of collagen biosynthetic process, positive regulation of collagen biosynthetic process, protein localization in organelle, protein localization in nucleus, cellular protein localization, wound healing, regulation of phosphorylation, positive regulation of phosphorylation, homeostatic process, fibrinolysis, regulation of apoptosis,regulation of programmed cell death, positive regulation of catalytic activity, regulation of ion transport, positive regulation of ion transport, positive regulation of caspase activity, regulation of caspase activity, positive regulation of molecular function, regulation of multicellular organismal metabolic process, positive regulation of multicellular organismal metabolic process, establishment of protein localization, positive regulation of phosphate metabolic process, intracellular transport, chemical homeostasis, ion homeostasis, coagulation, regulation of coagulation,negative regulation of coagulation, positive regulation of coagulation, regulation of body fluid levels, positive regulation of transport, nuclear transport, nuclear import, regulation of phosphorus metabolic process, release of sequestered calcium ion into cytosol, positive regulation of multicellular organismal process, negative regulation of multicellular organismal process, positive regulation of protein metabolic process, regulation of release of sequestered calcium ion into cytosol, positive regulation of release of sequestered calcium ion into cytosol, regulation of sequestering of calcium ion, negative regulation of sequestering of calcium ion, regulation of hydrolase activity,positive regulation of hydrolase activity, cytosolic calcium ion homeostasis, regulation of calcium ion transport, positive regulation of calcium ion transport, regulation of peptidase activity, regulation of endopeptidase activity, metal ion homeostasis, di-, tri-valent inorganic cation homeostasis, calcium ion homeostasis, cation homeostasis, cellular chemical homeostasis, cytosolic calcium ion transport, calcium ion transport into cytosol, cellular macromolecule localization,
相关产品: YT5126,YT3862,YC0077,KA3977C,KA3520C
细胞定位: Secreted, extracellular space.
组织表达: Expressed by the liver and secreted in plasma.