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Cleaved-Lamin A (N231) Cell-Based Colorimetric ELISA Kit
商品货号: PLA001725
ELISA
¥600元
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说明书
商品描述
  • 发货日期: 14
  • 基因名称: LMNA
  • Human_gene_id: 4000
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4000
  • Human_swiss_prot_no: P02545
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P02545/entry
  • Mouse_swiss_prot_no: P48678
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P48678
  • Rat_swiss_prot_no: P48679
  • Rat_swiss_link: http://www.uniprot.org/uniprot/O54941P48679
  • 储存: 2-8°C/6 months
  • 说明书: KA3930C.pdf
  • 其他名称: Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
  • 功能: nucleus organization, nuclear envelope organization, gamete generation, spermatogenesis, muscle organ development, endomembrane organization, membrane organization, sexual reproduction, multicellular organism reproduction, male gamete generation, reproductive process in a multicellular organism,
  • 相关产品: YT2521,YT2520,YP0882,YP0485,YC0058,YC0057,KA4158C,KA3930C,KA3929C,KA1768C,KA1297C
  • 细胞定位: Nucleus . Nucleus envelope . Nucleus lamina. Nucleus, nucleoplasm. Nucleus matrix . Farnesylation of prelamin-A/C facilitates nuclear envelope targeting and subsequent cleavage by ZMPSTE24/FACE1 to remove the farnesyl group produces mature lamin-A/C, which can then be inserted into the nuclear lamina. EMD is required for proper localization of non-farnesylated prelamin-A/C.; [Isoform C]: Nucleus speckle .
  • 组织表达: In the arteries, prelamin-A/C accumulation is not observed in young healthy vessels but is prevalent in medial vascular smooth muscle cells (VSMCs) from aged individuals and in atherosclerotic lesions, where it often colocalizes with senescent and degenerate VSMCs. Prelamin-A/C expression increases with age and disease. In normal aging, the accumulation of prelamin-A/C is caused in part by the down-regulation of ZMPSTE24/FACE1 in response to oxidative stress.
  • 科研货号: PLA001725
Cleaved-Lamin A (N231) Cell-Based Colorimetric ELISA Kit
Catalog No PLA001725
Product information
  • 发货日期: 14
  • 基因名称: LMNA
  • Human_gene_id: 4000
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4000
  • Human_swiss_prot_no: P02545
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P02545/entry
  • Mouse_swiss_prot_no: P48678
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P48678
  • Rat_swiss_prot_no: P48679
  • Rat_swiss_link: http://www.uniprot.org/uniprot/O54941P48679
  • 储存: 2-8°C/6 months
  • 说明书: KA3930C.pdf
  • 其他名称: Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
  • 功能: nucleus organization, nuclear envelope organization, gamete generation, spermatogenesis, muscle organ development, endomembrane organization, membrane organization, sexual reproduction, multicellular organism reproduction, male gamete generation, reproductive process in a multicellular organism,
  • 相关产品: YT2521,YT2520,YP0882,YP0485,YC0058,YC0057,KA4158C,KA3930C,KA3929C,KA1768C,KA1297C
  • 细胞定位: Nucleus . Nucleus envelope . Nucleus lamina. Nucleus, nucleoplasm. Nucleus matrix . Farnesylation of prelamin-A/C facilitates nuclear envelope targeting and subsequent cleavage by ZMPSTE24/FACE1 to remove the farnesyl group produces mature lamin-A/C, which can then be inserted into the nuclear lamina. EMD is required for proper localization of non-farnesylated prelamin-A/C.; [Isoform C]: Nucleus speckle .
  • 组织表达: In the arteries, prelamin-A/C accumulation is not observed in young healthy vessels but is prevalent in medial vascular smooth muscle cells (VSMCs) from aged individuals and in atherosclerotic lesions, where it often colocalizes with senescent and degenerate VSMCs. Prelamin-A/C expression increases with age and disease. In normal aging, the accumulation of prelamin-A/C is caused in part by the down-regulation of ZMPSTE24/FACE1 in response to oxidative stress.
  • 科研货号: PLA001725
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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