其他名称： Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4)
功能： regulation of cell growth, urogenital system development, metanephros development, ureteric bud development,branching involved in ureteric bud morphogenesis, response to hypoxia, gastrulation with mouth forming second,morphogenesis of a branching structure, regulation of cytokine production, kidney development, regulation of protein amino acid phosphorylation, positive regulation of protein amino acid phosphorylation, morphogenesis of an epithelium, regionalization, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, protein complex assembly, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein serine/threonine kinase signaling pathway,transforming growth factor beta receptor signaling pathway, SMAD protein complex assembly, gastrulation, pattern specification process, negative regulation of cell proliferation, regulation of cell size, negative regulation of biosynthetic process, positive regulation of biosynthetic process, anterior/posterior pattern formation, positive regulation of signal transduction, positive regulation of macromolecule biosynthetic process, negative regulation of macromolecule biosynthetic process, positive regulation of phosphorus metabolic process, positive regulation of macromolecule metabolic process, negative regulation of macromolecule metabolic process, positive regulation of gene expression, negative regulation of gene expression, positive regulation of cell communication, regulation of epithelial to mesenchymal transition, positive regulation of epithelial to mesenchymal transition, positive regulation of cell development, regulation of cell morphogenesis involved in differentiation, positive regulation of cell morphogenesis involved in differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, negative regulation of transcription, regulation of transforming growth factor beta receptor signaling pathway, regulation of phosphate metabolic process, regulation of cell morphogenesis, neuron differentiation, negative regulation of cell growth, BMP signaling pathway, negative regulation of cellular biosynthetic process, positive regulation of cellular biosynthetic process, regulation of protein modification process, positive regulation of protein modification process,regulation of cellular protein metabolic process, positive regulation of cellular protein metabolic process, regulation of intracellular transport, positive regulation of intracellular transport, regulation of cellular component size, regulation of protein localization, regulation of transforming growth factor-beta2 production, regulation of intracellular protein transport, regulation of protein import into nucleus, translocation, positive regulation of protein import into nucleus, translocation, cellular macromolecular complex subunit organization, cellular macromolecular complex assembly, tube morphogenesis, tube development, regulation of growth, regulation of cell proliferation, regulation of protein import into nucleus, regulation of phosphorylation, positive regulation of phosphorylation, cellular protein complex assembly,macromolecular complex subunit organization, cell fate commitment, regulation of transcription, positive regulation of cell differentiation, negative regulation of cell size, negative regulation of transcription, DNA-dependent, positive regulation of transcription, DNA-dependent, negative regulation of growth, negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of phosphate metabolic process, positive regulation of transcription, positive regulation of transcription from RNA polymerase II promoter, regulation of nucleocytoplasmic transport, embryonic morphogenesis, neuron fate commitment, tissue morphogenesis, branching morphogenesis of a tube, positive regulation of transport, positive regulation of developmental process, regulation of binding, positive regulation of cellular component organization, negative regulation of nitrogen compound metabolic process, positive regulation of nitrogen compound metabolic process, regulation of phosphorus metabolic process, positive regulation of protein transport, regulation of protein transport, positive regulation of protein metabolic process, regulation of RNA metabolic process, negative regulation of RNA metabolic process, positive regulation of RNA metabolic process, palate development, regulation of cell development, regulation of cellular localization, regulation of SMAD protein nuclear translocation, positive regulation of SMAD protein nuclear translocation, regulation of pathway-restricted SMAD protein phosphorylation, SMAD protein signal transduction, epithelium development, epithelial tube morphogenesis, ureteric bud morphogenesis, macromolecular complex assembly, regulation of establishment of protein localization, protein complex biogenesis, response to oxygen levels,
相关产品： YT4337,YM0583,KA3716C,KE1372,KE1709
细胞定位： Cytoplasm . Nucleus . Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with R-SMAD (PubMed:15799969). PDPK1 prevents its nuclear translocation in response to TGF-beta (PubMed:17327236). .
其他名称： Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4)
功能： regulation of cell growth, urogenital system development, metanephros development, ureteric bud development,branching involved in ureteric bud morphogenesis, response to hypoxia, gastrulation with mouth forming second,morphogenesis of a branching structure, regulation of cytokine production, kidney development, regulation of protein amino acid phosphorylation, positive regulation of protein amino acid phosphorylation, morphogenesis of an epithelium, regionalization, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, protein complex assembly, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein serine/threonine kinase signaling pathway,transforming growth factor beta receptor signaling pathway, SMAD protein complex assembly, gastrulation, pattern specification process, negative regulation of cell proliferation, regulation of cell size, negative regulation of biosynthetic process, positive regulation of biosynthetic process, anterior/posterior pattern formation, positive regulation of signal transduction, positive regulation of macromolecule biosynthetic process, negative regulation of macromolecule biosynthetic process, positive regulation of phosphorus metabolic process, positive regulation of macromolecule metabolic process, negative regulation of macromolecule metabolic process, positive regulation of gene expression, negative regulation of gene expression, positive regulation of cell communication, regulation of epithelial to mesenchymal transition, positive regulation of epithelial to mesenchymal transition, positive regulation of cell development, regulation of cell morphogenesis involved in differentiation, positive regulation of cell morphogenesis involved in differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, negative regulation of transcription, regulation of transforming growth factor beta receptor signaling pathway, regulation of phosphate metabolic process, regulation of cell morphogenesis, neuron differentiation, negative regulation of cell growth, BMP signaling pathway, negative regulation of cellular biosynthetic process, positive regulation of cellular biosynthetic process, regulation of protein modification process, positive regulation of protein modification process,regulation of cellular protein metabolic process, positive regulation of cellular protein metabolic process, regulation of intracellular transport, positive regulation of intracellular transport, regulation of cellular component size, regulation of protein localization, regulation of transforming growth factor-beta2 production, regulation of intracellular protein transport, regulation of protein import into nucleus, translocation, positive regulation of protein import into nucleus, translocation, cellular macromolecular complex subunit organization, cellular macromolecular complex assembly, tube morphogenesis, tube development, regulation of growth, regulation of cell proliferation, regulation of protein import into nucleus, regulation of phosphorylation, positive regulation of phosphorylation, cellular protein complex assembly,macromolecular complex subunit organization, cell fate commitment, regulation of transcription, positive regulation of cell differentiation, negative regulation of cell size, negative regulation of transcription, DNA-dependent, positive regulation of transcription, DNA-dependent, negative regulation of growth, negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of phosphate metabolic process, positive regulation of transcription, positive regulation of transcription from RNA polymerase II promoter, regulation of nucleocytoplasmic transport, embryonic morphogenesis, neuron fate commitment, tissue morphogenesis, branching morphogenesis of a tube, positive regulation of transport, positive regulation of developmental process, regulation of binding, positive regulation of cellular component organization, negative regulation of nitrogen compound metabolic process, positive regulation of nitrogen compound metabolic process, regulation of phosphorus metabolic process, positive regulation of protein transport, regulation of protein transport, positive regulation of protein metabolic process, regulation of RNA metabolic process, negative regulation of RNA metabolic process, positive regulation of RNA metabolic process, palate development, regulation of cell development, regulation of cellular localization, regulation of SMAD protein nuclear translocation, positive regulation of SMAD protein nuclear translocation, regulation of pathway-restricted SMAD protein phosphorylation, SMAD protein signal transduction, epithelium development, epithelial tube morphogenesis, ureteric bud morphogenesis, macromolecular complex assembly, regulation of establishment of protein localization, protein complex biogenesis, response to oxygen levels,
相关产品： YT4337,YM0583,KA3716C,KE1372,KE1709
细胞定位： Cytoplasm . Nucleus . Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with R-SMAD (PubMed:15799969). PDPK1 prevents its nuclear translocation in response to TGF-beta (PubMed:17327236). .
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