功能： apoptosis, induction of apoptosis, intracellular signaling cascade, cell death, induction of apoptosis by extracellular signals, regulation of cell death, positive regulation of cell death, programmed cell death, induction of programmed cell death, death, regulation of Rho protein signal transduction, regulation of apoptosis, positive regulation of apoptosis,regulation of programmed cell death, positive regulation of programmed cell death, regulation of Ras protein signal transduction, regulation of small GTPase mediated signal transduction,
相关产品： YT0161,KA3695C,KE1372,KE1709
细胞定位： Cytoplasm, cytosol . Cytoplasm . Cytoplasm, cell cortex . Nucleus . Membrane ; Peripheral membrane protein . Colocalizes with the actin cytoskeleton at the cell cortex. .
组织表达： Detected in mammary gland (PubMed:9627117). Detected in heart (at protein level) (PubMed:11546812). Expressed as a 5.3 kb transcript in hematopoietic cells, skeletal muscle, lung, heart, estrogen-responsive reproductive tissues, including breast ductal epithelium. Also found in testis and breast cancer cell lines. Predominantly expressed as a 10 kb transcript in the heart and at lower levels in the lung, placenta, kidney, pancreas, skeletal muscle and liver. Transcripts of between 6-9 kb are also expressed in myeloid and lymphoid lineages, a variety of epithelial tissues, and in skeletal muscle.
功能： apoptosis, induction of apoptosis, intracellular signaling cascade, cell death, induction of apoptosis by extracellular signals, regulation of cell death, positive regulation of cell death, programmed cell death, induction of programmed cell death, death, regulation of Rho protein signal transduction, regulation of apoptosis, positive regulation of apoptosis,regulation of programmed cell death, positive regulation of programmed cell death, regulation of Ras protein signal transduction, regulation of small GTPase mediated signal transduction,
相关产品： YT0161,KA3695C,KE1372,KE1709
细胞定位： Cytoplasm, cytosol . Cytoplasm . Cytoplasm, cell cortex . Nucleus . Membrane ; Peripheral membrane protein . Colocalizes with the actin cytoskeleton at the cell cortex. .
组织表达： Detected in mammary gland (PubMed:9627117). Detected in heart (at protein level) (PubMed:11546812). Expressed as a 5.3 kb transcript in hematopoietic cells, skeletal muscle, lung, heart, estrogen-responsive reproductive tissues, including breast ductal epithelium. Also found in testis and breast cancer cell lines. Predominantly expressed as a 10 kb transcript in the heart and at lower levels in the lung, placenta, kidney, pancreas, skeletal muscle and liver. Transcripts of between 6-9 kb are also expressed in myeloid and lymphoid lineages, a variety of epithelial tissues, and in skeletal muscle.
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