功能： RNA processing, mRNA processing, RNA modification, negative regulation of macromolecule metabolic process,negative regulation of gene expression, mRNA metabolic process, gene silencing, base conversion or substitution editing, gene silencing by RNA,
相关产品： YT0118,KA3647C,KE1372,KE1709
细胞定位： [Isoform 1]: Cytoplasm . Nucleus . Shuttles between the cytoplasm and nucleus (PubMed:7565688, PubMed:24753571). Nuclear import is mediated by TNPO1 (PubMed:24753571). .; [Isoform 5]: Cytoplasm . Nucleus . Nucleus, nucleolus . Predominantly nuclear but can shuttle between nucleus and cytoplasm. TNPO1 can mediate its nuclear import whereas XPO5 can mediate its nuclear export. .
组织表达： Ubiquitously expressed, highest levels were found in brain and lung (PubMed:7972084). Isoform 5 is expressed at higher levels in astrocytomas as compared to normal brain tissue and expression increases strikingly with the severity of the tumor, being higher in the most aggressive tumors.
功能： RNA processing, mRNA processing, RNA modification, negative regulation of macromolecule metabolic process,negative regulation of gene expression, mRNA metabolic process, gene silencing, base conversion or substitution editing, gene silencing by RNA,
相关产品： YT0118,KA3647C,KE1372,KE1709
细胞定位： [Isoform 1]: Cytoplasm . Nucleus . Shuttles between the cytoplasm and nucleus (PubMed:7565688, PubMed:24753571). Nuclear import is mediated by TNPO1 (PubMed:24753571). .; [Isoform 5]: Cytoplasm . Nucleus . Nucleus, nucleolus . Predominantly nuclear but can shuttle between nucleus and cytoplasm. TNPO1 can mediate its nuclear import whereas XPO5 can mediate its nuclear export. .
组织表达： Ubiquitously expressed, highest levels were found in brain and lung (PubMed:7972084). Isoform 5 is expressed at higher levels in astrocytomas as compared to normal brain tissue and expression increases strikingly with the severity of the tumor, being higher in the most aggressive tumors.
在线咨询
湘公网安备