其他名称： Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein)
功能： microtubule cytoskeleton organization, M phase, double-strand break repair via homologous recombination,recombinational repair, cytokinesis, oocyte maturation, in utero embryonic development, blastocyst development,blastocyst growth, inner cell mass cell proliferation, immune system development, reproductive developmental process, DNA metabolic process, DNA replication, DNA-dependent DNA replication, regulation of DNA replication, DNA repair, nucleotide-excision repair, double-strand break repair, DNA recombination, regulation of transcription, DNA-dependent, induction of apoptosis, response to DNA damage stimulus, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, cytoskeleton organization, microtubule-based process, cell cycle, regulation of S phase of mitotic cell cycle, centrosome cycle, meiosis, male meiosis, male meiosis I,intracellular signaling cascade, gamete generation, germ cell development, spermatogenesis, female gamete generation, regulation of mitotic cell cycle, sex differentiation, aging, cell aging, response to nutrient, negative regulation of DNA replication, cell proliferation, negative regulation of cell proliferation, gonad development, female gonad development, induction of apoptosis by intracellular signals, DNA damage response, signal transduction resulting in induction of apoptosis, response to radiation, response to UV, response to light stimulus, response to abiotic stimulus, response to endogenous stimulus, response to hormone stimulus, embryonic development ending in birth or egg hatching, negative regulation of biosynthetic process, response to extracellular stimulus, oocyte differentiation, response to organic substance, response to X-ray, response to ionizing radiation, response to UV-C,response to gamma radiation, negative regulation of macromolecule biosynthetic process, regulation of cell cycle process, negative regulation of macromolecule metabolic process, regulation of cell death, positive regulation of cell death, induction of programmed cell death, response to organic cyclic substance, sexual reproduction, developmental maturation, cell cycle process, cell cycle phase, hemopoiesis, DNA damage response, signal transduction by p53 class mediator, mammary gland development, microtubule organizing center organization, negative regulation of cellular biosynthetic process, response to nutrient levels, multicellular organism reproduction, cytokinesis during cell cycle,regulation of S phase, cellular response to stress, response to genistein, regulation of mammary gland epithelial cell proliferation, negative regulation of mammary gland epithelial cell proliferation, hemocyte proliferation, multicellular organism growth, growth, regulation of cell proliferation, DNA damage response, signal transduction, DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis, DNA damage response, signal transduction resulting in transcription, regulation of apoptosis, chordate embryonic development, positive regulation of apoptosis, regulation of programmed cell death, positive regulation of programmed cell death, response to estrogen stimulus, maintenance of fidelity during DNA-dependent DNA replication, development of primary sexual characteristics, regulation of transcription, positive regulation of cell cycle, positive regulation of mitotic cell cycle,negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, development of primary female sexual characteristics, female sex differentiation, male gamete generation, cell maturation, oogenesis,replication fork protection, hemopoietic or lymphoid organ development, response to steroid hormone stimulus,developmental growth, oocyte development, reproductive structure development, reproductive process in a multicellular organism, reproductive cellular process, gland development, regulation of epithelial cell proliferation,negative regulation of epithelial cell proliferation, regulation of DNA metabolic process, negative regulation of DNA metabolic process, negative regulation of nitrogen compound metabolic process, regulation of RNA metabolic process,chromosome organization, centrosome organization, centrosome duplication, cell division, meiotic cell cycle, M phase of meiotic cell cycle, regulation of cell cycle,
相关产品： YT0520,YP0512,KA3626C,KE1372,KE1709
细胞定位： Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Colocalizes with ERCC5/XPG to nuclear foci following DNA replication stress. .
组织表达： Highest levels of expression in breast and thymus, with slightly lower levels in lung, ovary and spleen.
其他名称： Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein)
功能： microtubule cytoskeleton organization, M phase, double-strand break repair via homologous recombination,recombinational repair, cytokinesis, oocyte maturation, in utero embryonic development, blastocyst development,blastocyst growth, inner cell mass cell proliferation, immune system development, reproductive developmental process, DNA metabolic process, DNA replication, DNA-dependent DNA replication, regulation of DNA replication, DNA repair, nucleotide-excision repair, double-strand break repair, DNA recombination, regulation of transcription, DNA-dependent, induction of apoptosis, response to DNA damage stimulus, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, cytoskeleton organization, microtubule-based process, cell cycle, regulation of S phase of mitotic cell cycle, centrosome cycle, meiosis, male meiosis, male meiosis I,intracellular signaling cascade, gamete generation, germ cell development, spermatogenesis, female gamete generation, regulation of mitotic cell cycle, sex differentiation, aging, cell aging, response to nutrient, negative regulation of DNA replication, cell proliferation, negative regulation of cell proliferation, gonad development, female gonad development, induction of apoptosis by intracellular signals, DNA damage response, signal transduction resulting in induction of apoptosis, response to radiation, response to UV, response to light stimulus, response to abiotic stimulus, response to endogenous stimulus, response to hormone stimulus, embryonic development ending in birth or egg hatching, negative regulation of biosynthetic process, response to extracellular stimulus, oocyte differentiation, response to organic substance, response to X-ray, response to ionizing radiation, response to UV-C,response to gamma radiation, negative regulation of macromolecule biosynthetic process, regulation of cell cycle process, negative regulation of macromolecule metabolic process, regulation of cell death, positive regulation of cell death, induction of programmed cell death, response to organic cyclic substance, sexual reproduction, developmental maturation, cell cycle process, cell cycle phase, hemopoiesis, DNA damage response, signal transduction by p53 class mediator, mammary gland development, microtubule organizing center organization, negative regulation of cellular biosynthetic process, response to nutrient levels, multicellular organism reproduction, cytokinesis during cell cycle,regulation of S phase, cellular response to stress, response to genistein, regulation of mammary gland epithelial cell proliferation, negative regulation of mammary gland epithelial cell proliferation, hemocyte proliferation, multicellular organism growth, growth, regulation of cell proliferation, DNA damage response, signal transduction, DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis, DNA damage response, signal transduction resulting in transcription, regulation of apoptosis, chordate embryonic development, positive regulation of apoptosis, regulation of programmed cell death, positive regulation of programmed cell death, response to estrogen stimulus, maintenance of fidelity during DNA-dependent DNA replication, development of primary sexual characteristics, regulation of transcription, positive regulation of cell cycle, positive regulation of mitotic cell cycle,negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, development of primary female sexual characteristics, female sex differentiation, male gamete generation, cell maturation, oogenesis,replication fork protection, hemopoietic or lymphoid organ development, response to steroid hormone stimulus,developmental growth, oocyte development, reproductive structure development, reproductive process in a multicellular organism, reproductive cellular process, gland development, regulation of epithelial cell proliferation,negative regulation of epithelial cell proliferation, regulation of DNA metabolic process, negative regulation of DNA metabolic process, negative regulation of nitrogen compound metabolic process, regulation of RNA metabolic process,chromosome organization, centrosome organization, centrosome duplication, cell division, meiotic cell cycle, M phase of meiotic cell cycle, regulation of cell cycle,
相关产品： YT0520,YP0512,KA3626C,KE1372,KE1709
细胞定位： Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Colocalizes with ERCC5/XPG to nuclear foci following DNA replication stress. .
组织表达： Highest levels of expression in breast and thymus, with slightly lower levels in lung, ovary and spleen.
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