其他名称: E3 SUMO-protein ligase PIAS4 (EC 6.3.2.-) (PIASy) (Protein inhibitor of activated STAT protein 4) (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma)
功能: negative regulation of transcription from RNA polymerase II promoter, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, proteolysis, cell surface receptor linked signal transduction, macromolecule catabolic process, negative regulation of biosynthetic process, negative regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, negative regulation of macromolecule metabolic process, negative regulation of gene expression, Wnt receptor signaling pathway, negative regulation of transcription, protein sumoylation, modification-dependent protein catabolic process, protein catabolic process, negative regulation of cellular biosynthetic process, regulation of protein modification process, positive regulation of protein modification process, regulation of cellular protein metabolic process, positive regulation of cellular protein metabolic process, protein modification by small protein conjugation, regulation of protein sumoylation,positive regulation of protein sumoylation, modification-dependent macromolecule catabolic process, cellular protein catabolic process, cellular macromolecule catabolic process, regulation of transcription, negative regulation of transcription, DNA-dependent, negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, negative regulation of nitrogen compound metabolic process, positive regulation of protein metabolic process, regulation of RNA metabolic process, negative regulation of RNA metabolic process, proteolysis involved in cellular protein catabolic process, protein modification by small protein conjugation or removal,
相关产品: YT3720,KA3413C,KE1372,KE1709
细胞定位: Nucleus, PML body . Colocalizes with SUMO1 and TCF7L2/TCF4 and LEF1 in a subset of PML (promyelocytic leukemia) nuclear bodies. .
组织表达: Highly expressed in testis and, at lower levels, in spleen, prostate, ovary, colon and peripheral blood leukocytes.
其他名称: E3 SUMO-protein ligase PIAS4 (EC 6.3.2.-) (PIASy) (Protein inhibitor of activated STAT protein 4) (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma)
功能: negative regulation of transcription from RNA polymerase II promoter, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, proteolysis, cell surface receptor linked signal transduction, macromolecule catabolic process, negative regulation of biosynthetic process, negative regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, negative regulation of macromolecule metabolic process, negative regulation of gene expression, Wnt receptor signaling pathway, negative regulation of transcription, protein sumoylation, modification-dependent protein catabolic process, protein catabolic process, negative regulation of cellular biosynthetic process, regulation of protein modification process, positive regulation of protein modification process, regulation of cellular protein metabolic process, positive regulation of cellular protein metabolic process, protein modification by small protein conjugation, regulation of protein sumoylation,positive regulation of protein sumoylation, modification-dependent macromolecule catabolic process, cellular protein catabolic process, cellular macromolecule catabolic process, regulation of transcription, negative regulation of transcription, DNA-dependent, negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, negative regulation of nitrogen compound metabolic process, positive regulation of protein metabolic process, regulation of RNA metabolic process, negative regulation of RNA metabolic process, proteolysis involved in cellular protein catabolic process, protein modification by small protein conjugation or removal,
相关产品: YT3720,KA3413C,KE1372,KE1709
细胞定位: Nucleus, PML body . Colocalizes with SUMO1 and TCF7L2/TCF4 and LEF1 in a subset of PML (promyelocytic leukemia) nuclear bodies. .
组织表达: Highly expressed in testis and, at lower levels, in spleen, prostate, ovary, colon and peripheral blood leukocytes.