其他名称： E3 SUMO-protein ligase PIAS2 (EC 6.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (Msx-interacting zinc finger protein) (Miz1) (PIAS-NY protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2)
功能： transcription, regulation of transcription, DNA-dependent, proteolysis, intracellular signaling cascade, macromolecule catabolic process, positive regulation of biosynthetic process, positive regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, positive regulation of gene expression, modification-dependent protein catabolic process, protein catabolic process, steroid hormone receptor signaling pathway,androgen receptor signaling pathway, intracellular receptor-mediated signaling pathway, positive regulation of cellular biosynthetic process, modification-dependent macromolecule catabolic process, cellular protein catabolic process,cellular macromolecule catabolic process, regulation of transcription, positive regulation of transcription, DNA-dependent, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of transcription, positive regulation of nitrogen compound metabolic process, regulation of RNA metabolic process, positive regulation of RNA metabolic process, proteolysis involved in cellular protein catabolic process,
相关产品： YT3719,KA3411C,KE1372,KE1709
细胞定位： Nucleus speckle . Nucleus, PML body . Nucleus . Colocalizes at least partially with promyelocytic leukemia nuclear bodies (PML NBs) (PubMed:22406621). Colocalizes with SUMO1 in nuclear granules (By similarity). .
组织表达： Mainly expressed in testis. Isoform 3 is expressed predominantly in adult testis, weakly in pancreas, embryonic testis and sperm, and at very low levels in other organs.
其他名称： E3 SUMO-protein ligase PIAS2 (EC 6.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (Msx-interacting zinc finger protein) (Miz1) (PIAS-NY protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2)
功能： transcription, regulation of transcription, DNA-dependent, proteolysis, intracellular signaling cascade, macromolecule catabolic process, positive regulation of biosynthetic process, positive regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, positive regulation of gene expression, modification-dependent protein catabolic process, protein catabolic process, steroid hormone receptor signaling pathway,androgen receptor signaling pathway, intracellular receptor-mediated signaling pathway, positive regulation of cellular biosynthetic process, modification-dependent macromolecule catabolic process, cellular protein catabolic process,cellular macromolecule catabolic process, regulation of transcription, positive regulation of transcription, DNA-dependent, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of transcription, positive regulation of nitrogen compound metabolic process, regulation of RNA metabolic process, positive regulation of RNA metabolic process, proteolysis involved in cellular protein catabolic process,
相关产品： YT3719,KA3411C,KE1372,KE1709
细胞定位： Nucleus speckle . Nucleus, PML body . Nucleus . Colocalizes at least partially with promyelocytic leukemia nuclear bodies (PML NBs) (PubMed:22406621). Colocalizes with SUMO1 in nuclear granules (By similarity). .
组织表达： Mainly expressed in testis. Isoform 3 is expressed predominantly in adult testis, weakly in pancreas, embryonic testis and sperm, and at very low levels in other organs.
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