其他名称： 78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)
功能： anti-apoptosis, ER overload response, ER-nuclear signaling pathway, cellular response to starvation, response to extracellular stimulus, negative regulation of peptidase activity, regulation of cell death, response to nutrient levels,cellular response to extracellular stimulus, cellular response to nutrient levels, cellular response to stress, response to endoplasmic reticulum stress, cellular response to glucose starvation, response to starvation, regulation of apoptosis,negative regulation of apoptosis, regulation of programmed cell death, negative regulation of programmed cell death,negative regulation of catalytic activity, negative regulation of caspase activity, regulation of caspase activity, negative regulation of molecular function, regulation of hydrolase activity, negative regulation of hydrolase activity, regulation of peptidase activity, regulation of endopeptidase activity, negative regulation of cell death,
相关产品： YT5858,YT2245,YM3508,YM3505,KA3283C
细胞定位： Endoplasmic reticulum lumen . Melanosome . Cytoplasm . Cell surface . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545). Localizes to the cell surface of epithelial cells in response to high levels of free iron (PubMed:20484814, PubMed:24355926, PubMed:27159390). .
其他名称： 78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)
功能： anti-apoptosis, ER overload response, ER-nuclear signaling pathway, cellular response to starvation, response to extracellular stimulus, negative regulation of peptidase activity, regulation of cell death, response to nutrient levels,cellular response to extracellular stimulus, cellular response to nutrient levels, cellular response to stress, response to endoplasmic reticulum stress, cellular response to glucose starvation, response to starvation, regulation of apoptosis,negative regulation of apoptosis, regulation of programmed cell death, negative regulation of programmed cell death,negative regulation of catalytic activity, negative regulation of caspase activity, regulation of caspase activity, negative regulation of molecular function, regulation of hydrolase activity, negative regulation of hydrolase activity, regulation of peptidase activity, regulation of endopeptidase activity, negative regulation of cell death,
相关产品： YT5858,YT2245,YM3508,YM3505,KA3283C
细胞定位： Endoplasmic reticulum lumen . Melanosome . Cytoplasm . Cell surface . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545). Localizes to the cell surface of epithelial cells in response to high levels of free iron (PubMed:20484814, PubMed:24355926, PubMed:27159390). .
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