其他名称： Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1)
功能： skeletal system development, ossification, osteoblast differentiation, regulation of nucleotide metabolic process, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, negative regulation of adenylate cyclase activity, gamma-aminobutyric acid signaling pathway, regulation of cyclic nucleotide metabolic process, regulation of cyclic nucleotide biosynthetic process, regulation of nucleotide biosynthetic process, regulation of cAMP metabolic process, regulation of cAMP biosynthetic process, regulation of cyclase activity, negative regulation of cyclase activity, negative regulation of catalytic activity, negative regulation of molecular function, regulation of adenylate cyclase activity, regulation of lyase activity, negative regulation of lyase activity, bone development,
相关产品： YT1829,YT1828,KA3265C,KE1372,KE1709
细胞定位： Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell projection, dendrite . Colocalizes with ATF4 in hippocampal neuron dendritic membranes (By similarity). Coexpression of GABBR1 and GABBR2 is required for GABBR1 maturation and transport to the plasma membrane (PubMed:15617512). .; [Isoform 1E]: Secreted .
组织表达： Highly expressed in brain (PubMed:9844003, PubMed:9753614, PubMed:9872744). Weakly expressed in heart, small intestine and uterus. Isoform 1A: Mainly expressed in granular cell and molecular layer (PubMed:9844003). Isoform 1B: Mainly expressed in Purkinje cells (PubMed:9844003). Isoform 1E: Predominantly expressed in peripheral tissues as kidney, lung, trachea, colon, small intestine, stomach, bone marrow, thymus and mammary gland (PubMed:10906333).
其他名称： Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1)
功能： skeletal system development, ossification, osteoblast differentiation, regulation of nucleotide metabolic process, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, negative regulation of adenylate cyclase activity, gamma-aminobutyric acid signaling pathway, regulation of cyclic nucleotide metabolic process, regulation of cyclic nucleotide biosynthetic process, regulation of nucleotide biosynthetic process, regulation of cAMP metabolic process, regulation of cAMP biosynthetic process, regulation of cyclase activity, negative regulation of cyclase activity, negative regulation of catalytic activity, negative regulation of molecular function, regulation of adenylate cyclase activity, regulation of lyase activity, negative regulation of lyase activity, bone development,
相关产品： YT1829,YT1828,KA3265C,KE1372,KE1709
细胞定位： Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell projection, dendrite . Colocalizes with ATF4 in hippocampal neuron dendritic membranes (By similarity). Coexpression of GABBR1 and GABBR2 is required for GABBR1 maturation and transport to the plasma membrane (PubMed:15617512). .; [Isoform 1E]: Secreted .
组织表达： Highly expressed in brain (PubMed:9844003, PubMed:9753614, PubMed:9872744). Weakly expressed in heart, small intestine and uterus. Isoform 1A: Mainly expressed in granular cell and molecular layer (PubMed:9844003). Isoform 1B: Mainly expressed in Purkinje cells (PubMed:9844003). Isoform 1E: Predominantly expressed in peripheral tissues as kidney, lung, trachea, colon, small intestine, stomach, bone marrow, thymus and mammary gland (PubMed:10906333).
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