功能： MAPKKK cascade, skeletal system development, protein amino acid phosphorylation, phosphorus metabolic process,phosphate metabolic process, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, intracellular signaling cascade,protein kinase cascade, JAK-STAT cascade, positive regulation of cell proliferation, regulation of cell size, fibroblast growth factor receptor signaling pathway, cell growth, phosphorylation, regulation of cellular component size, growth,regulation of cell proliferation,
相关产品： YT1701,KA3259C,KE1372,KE1709
细胞定位： [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle. Endoplasmic reticulum. The activated receptor is rapidly internalized and degraded. Detected in intracellular vesicles after internalization of the autophosphorylated receptor.; [Isoform 2]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 3]: Secreted.; [Isoform 4]: Cell membrane ; Single-pass type I membrane protein .
组织表达： Expressed in brain, kidney and testis. Very low or no expression in spleen, heart, and muscle. In 20- to 22-week old fetuses it is expressed at high level in kidney, lung, small intestine and brain, and to a lower degree in spleen, liver, and muscle. Isoform 2 is detected in epithelial cells. Isoform 1 is not detected in epithelial cells. Isoform 1 and isoform 2 are detected in fibroblastic cells.
功能： MAPKKK cascade, skeletal system development, protein amino acid phosphorylation, phosphorus metabolic process,phosphate metabolic process, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, intracellular signaling cascade,protein kinase cascade, JAK-STAT cascade, positive regulation of cell proliferation, regulation of cell size, fibroblast growth factor receptor signaling pathway, cell growth, phosphorylation, regulation of cellular component size, growth,regulation of cell proliferation,
相关产品： YT1701,KA3259C,KE1372,KE1709
细胞定位： [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle. Endoplasmic reticulum. The activated receptor is rapidly internalized and degraded. Detected in intracellular vesicles after internalization of the autophosphorylated receptor.; [Isoform 2]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 3]: Secreted.; [Isoform 4]: Cell membrane ; Single-pass type I membrane protein .
组织表达： Expressed in brain, kidney and testis. Very low or no expression in spleen, heart, and muscle. In 20- to 22-week old fetuses it is expressed at high level in kidney, lung, small intestine and brain, and to a lower degree in spleen, liver, and muscle. Isoform 2 is detected in epithelial cells. Isoform 1 is not detected in epithelial cells. Isoform 1 and isoform 2 are detected in fibroblastic cells.
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