其他名称： Protein DJ-1 (EC 3.4.-.-) (Oncogene DJ1) (Parkinson disease protein 7)
功能： response to reactive oxygen species, neurotransmitter uptake, regulation of neurotransmitter levels, synaptic transmission, dopaminergic, oxygen and reactive oxygen species metabolic process, neurotransmitter transport,cellular ion homeostasis, response to oxidative stress, intracellular signaling cascade, small GTPase mediated signal transduction, Ras protein signal transduction, cell-cell signaling, synaptic transmission, nerve-nerve synaptic transmission, behavior, locomotory behavior, adult locomotory behavior, response to inorganic substance, amine transport, monoamine transport, organic alcohol transport, dopamine transport, transmission of nerve impulse,cellular homeostasis, adult behavior, regulation of membrane potential, response to drug, response to hydrogen peroxide, homeostatic process, hydrogen peroxide metabolic process, chemical homeostasis, ion homeostasis,neurological system process, dopamine uptake, membrane depolarization, catecholamine uptake during transmission of nerve impulse, catecholamine transport, cellular chemical homeostasis, membrane hyperpolarization,
相关产品： YT3592,YT1354,KA3242C,KE1372,KE1709
细胞定位： Cell membrane ; Lipid-anchor . Cytoplasm . Nucleus . Membrane raft . Mitochondrion . Endoplasmic reticulum . Under normal conditions, located predominantly in the cytoplasm and, to a lesser extent, in the nucleus and mitochondrion. Translocates to the mitochondrion and subsequently to the nucleus in response to oxidative stress and exerts an increased cytoprotective effect against oxidative damage (PubMed:18711745). Detected in tau inclusions in brains from neurodegenerative disease patients (PubMed:14705119). Membrane raft localization in astrocytes and neuronal cells requires palmitoylation. .
组织表达： Highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart. Detected at slightly lower levels in placenta and brain (at protein level). Detected in astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa. Expressed by pancreatic islets at higher levels than surrounding exocrine tissues (PubMed:22611253).
其他名称： Protein DJ-1 (EC 3.4.-.-) (Oncogene DJ1) (Parkinson disease protein 7)
功能： response to reactive oxygen species, neurotransmitter uptake, regulation of neurotransmitter levels, synaptic transmission, dopaminergic, oxygen and reactive oxygen species metabolic process, neurotransmitter transport,cellular ion homeostasis, response to oxidative stress, intracellular signaling cascade, small GTPase mediated signal transduction, Ras protein signal transduction, cell-cell signaling, synaptic transmission, nerve-nerve synaptic transmission, behavior, locomotory behavior, adult locomotory behavior, response to inorganic substance, amine transport, monoamine transport, organic alcohol transport, dopamine transport, transmission of nerve impulse,cellular homeostasis, adult behavior, regulation of membrane potential, response to drug, response to hydrogen peroxide, homeostatic process, hydrogen peroxide metabolic process, chemical homeostasis, ion homeostasis,neurological system process, dopamine uptake, membrane depolarization, catecholamine uptake during transmission of nerve impulse, catecholamine transport, cellular chemical homeostasis, membrane hyperpolarization,
相关产品： YT3592,YT1354,KA3242C,KE1372,KE1709
细胞定位： Cell membrane ; Lipid-anchor . Cytoplasm . Nucleus . Membrane raft . Mitochondrion . Endoplasmic reticulum . Under normal conditions, located predominantly in the cytoplasm and, to a lesser extent, in the nucleus and mitochondrion. Translocates to the mitochondrion and subsequently to the nucleus in response to oxidative stress and exerts an increased cytoprotective effect against oxidative damage (PubMed:18711745). Detected in tau inclusions in brains from neurodegenerative disease patients (PubMed:14705119). Membrane raft localization in astrocytes and neuronal cells requires palmitoylation. .
组织表达： Highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart. Detected at slightly lower levels in placenta and brain (at protein level). Detected in astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa. Expressed by pancreatic islets at higher levels than surrounding exocrine tissues (PubMed:22611253).
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