功能： cell morphogenesis, cytoskeleton organization, actin filament organization, cytoskeletal anchoring at plasma membrane, cell adhesion, leukocyte adhesion, establishment or maintenance of cell polarity, protein localization,regulation of cell shape, cell-cell adhesion, membrane docking, regulation of cell morphogenesis, biological adhesion,membrane to membrane docking, actin filament-based process, actin cytoskeleton organization, epithelial cell differentiation, maintenance of protein location in cell, cellular component morphogenesis, establishment or maintenance of apical/basal cell polarity, maintenance of protein location, actin filament bundle formation,maintenance of location, maintenance of location in cell, epithelium development,
细胞定位： Apical cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection . Cell projection, microvillus membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Cell projection, microvillus . Localization to the apical membrane of parietal cells depends on the interaction with PALS1. Localizes to cell extensions and peripheral processes of astrocytes (By similarity). Microvillar peripheral membrane protein (cytoplasmic side). .
组织表达： Expressed in cerebral cortex, basal ganglia, hippocampus, hypophysis, and optic nerve. Weakly expressed in brain stem and diencephalon. Stronger expression was detected in gray matter of frontal lobe compared to white matter (at protein level). Component of the microvilli of intestinal epithelial cells. Preferentially expressed in astrocytes of hippocampus, frontal cortex, thalamus, parahippocampal cortex, amygdala, insula, and corpus callosum. Not detected in neurons in most tissues studied.
功能： cell morphogenesis, cytoskeleton organization, actin filament organization, cytoskeletal anchoring at plasma membrane, cell adhesion, leukocyte adhesion, establishment or maintenance of cell polarity, protein localization,regulation of cell shape, cell-cell adhesion, membrane docking, regulation of cell morphogenesis, biological adhesion,membrane to membrane docking, actin filament-based process, actin cytoskeleton organization, epithelial cell differentiation, maintenance of protein location in cell, cellular component morphogenesis, establishment or maintenance of apical/basal cell polarity, maintenance of protein location, actin filament bundle formation,maintenance of location, maintenance of location in cell, epithelium development,
细胞定位： Apical cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection . Cell projection, microvillus membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Cell projection, microvillus . Localization to the apical membrane of parietal cells depends on the interaction with PALS1. Localizes to cell extensions and peripheral processes of astrocytes (By similarity). Microvillar peripheral membrane protein (cytoplasmic side). .
组织表达： Expressed in cerebral cortex, basal ganglia, hippocampus, hypophysis, and optic nerve. Weakly expressed in brain stem and diencephalon. Stronger expression was detected in gray matter of frontal lobe compared to white matter (at protein level). Component of the microvilli of intestinal epithelial cells. Preferentially expressed in astrocytes of hippocampus, frontal cortex, thalamus, parahippocampal cortex, amygdala, insula, and corpus callosum. Not detected in neurons in most tissues studied.
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