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Phospho PAK1 (S204) Cell-Based Colorimetric ELISA Kit
商品货号: PLA000715
ELISA
¥600元
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说明书
商品描述
  • 发货日期: 14
  • 基因名称: PAK1
  • Human_gene_id: 5058
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5058
  • Human_swiss_prot_no: Q13153
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q13153/entry
  • Mouse_swiss_prot_no: O88643
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/O88643
  • Rat_swiss_prot_no: P35465
  • Rat_swiss_link: http://www.uniprot.org/uniprot/O54941P35465
  • 储存: 2-8°C/6 months
  • 说明书: KA1713C.pdf
  • 其他名称: Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)
  • 功能: MAPKKK cascade, regulation of protein amino acid phosphorylation, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, apoptosis, ER-nuclear signaling pathway, cytoskeleton organization,intracellular signaling cascade, protein kinase cascade, cell death, regulation of protein kinase cascade, programmed cell death, death, phosphorylation, regulation of phosphate metabolic process, regulation of protein modification process, regulation of cellular protein metabolic process, positive regulation of kinase activity, regulation of phosphorylation, positive regulation of catalytic activity, regulation of MAP kinase activity, positive regulation of MAP kinase activity, regulation of MAPKKK cascade, regulation of JUN kinase activity, positive regulation of JUN kinase activity, regulation of kinase activity, positive regulation of molecular function, regulation of protein kinase activity,positive regulation of protein kinase activity, regulation of JNK cascade, protein amino acid autophosphorylation,regulation of phosphorus metabolic process, regulation of transferase activity, positive regulation of transferase activity, regulation of stress-activated protein kinase signaling pathway, regulation of cellular response to stress,
  • 相关产品: YT3577,YT3576,YT3575,YP0794,YP0757,YP0666,KA4217C,KA1713C,KA1317C
  • 细胞定位: Cytoplasm . Cell junction, focal adhesion . Cell projection, lamellipodium . Cell membrane . Cell projection, ruffle membrane . Cell projection, invadopodium . Nucleus, nucleoplasm . Chromosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Colocalizes with RUFY3, F-actin and other core migration components in invadopodia at the cell periphery (PubMed:25766321). Recruited to the cell membrane by interaction with CDC42 and RAC1. Recruited to focal adhesions upon activation. Colocalized with CIB1 within membrane ruffles during cell spreading upon readhesion to fibronectin. Upon DNA damage, translocates to the nucleoplasm when phosphorylated at Thr-212 where is co-recruited with MORC2 on damaged chromatin (PubMed:23260667). Localization to the centrosome does not depend upon the presence of gamma-tubulin (PubMed:27012601). Localization of the active, but not inactive, protein to the adhesions and edge of lamellipodia is mediated by interaction with GIT1 (PubMed:11896197). .
  • 组织表达: Overexpressed in gastric cancer cells and tissues (at protein level) (PubMed:25766321).
  • 科研货号: PLA000715
Phospho PAK1 (S204) Cell-Based Colorimetric ELISA Kit
Catalog No PLA000715
Product information
  • 发货日期: 14
  • 基因名称: PAK1
  • Human_gene_id: 5058
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5058
  • Human_swiss_prot_no: Q13153
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q13153/entry
  • Mouse_swiss_prot_no: O88643
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/O88643
  • Rat_swiss_prot_no: P35465
  • Rat_swiss_link: http://www.uniprot.org/uniprot/O54941P35465
  • 储存: 2-8°C/6 months
  • 说明书: KA1713C.pdf
  • 其他名称: Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)
  • 功能: MAPKKK cascade, regulation of protein amino acid phosphorylation, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, apoptosis, ER-nuclear signaling pathway, cytoskeleton organization,intracellular signaling cascade, protein kinase cascade, cell death, regulation of protein kinase cascade, programmed cell death, death, phosphorylation, regulation of phosphate metabolic process, regulation of protein modification process, regulation of cellular protein metabolic process, positive regulation of kinase activity, regulation of phosphorylation, positive regulation of catalytic activity, regulation of MAP kinase activity, positive regulation of MAP kinase activity, regulation of MAPKKK cascade, regulation of JUN kinase activity, positive regulation of JUN kinase activity, regulation of kinase activity, positive regulation of molecular function, regulation of protein kinase activity,positive regulation of protein kinase activity, regulation of JNK cascade, protein amino acid autophosphorylation,regulation of phosphorus metabolic process, regulation of transferase activity, positive regulation of transferase activity, regulation of stress-activated protein kinase signaling pathway, regulation of cellular response to stress,
  • 相关产品: YT3577,YT3576,YT3575,YP0794,YP0757,YP0666,KA4217C,KA1713C,KA1317C
  • 细胞定位: Cytoplasm . Cell junction, focal adhesion . Cell projection, lamellipodium . Cell membrane . Cell projection, ruffle membrane . Cell projection, invadopodium . Nucleus, nucleoplasm . Chromosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Colocalizes with RUFY3, F-actin and other core migration components in invadopodia at the cell periphery (PubMed:25766321). Recruited to the cell membrane by interaction with CDC42 and RAC1. Recruited to focal adhesions upon activation. Colocalized with CIB1 within membrane ruffles during cell spreading upon readhesion to fibronectin. Upon DNA damage, translocates to the nucleoplasm when phosphorylated at Thr-212 where is co-recruited with MORC2 on damaged chromatin (PubMed:23260667). Localization to the centrosome does not depend upon the presence of gamma-tubulin (PubMed:27012601). Localization of the active, but not inactive, protein to the adhesions and edge of lamellipodia is mediated by interaction with GIT1 (PubMed:11896197). .
  • 组织表达: Overexpressed in gastric cancer cells and tissues (at protein level) (PubMed:25766321).
  • 科研货号: PLA000715
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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