其他名称： DNA repair protein RAD51 homolog 1 (HsRAD51) (hRAD51) (RAD51 homolog A)
功能： M phase, double-strand break repair via homologous recombination, recombinational repair, DNA metabolic process,DNA replication, DNA-dependent DNA replication, DNA unwinding during replication, DNA repair, double-strand break repair, DNA recombination, mitotic recombination, protein complex assembly, response to DNA damage stimulus, cell cycle, meiosis, meiosis I, reciprocal meiotic recombination, positive regulation of macromolecule metabolic process, cell cycle process, cell cycle phase, DNA geometric change, DNA duplex unwinding, cellular response to stress,macromolecular complex subunit organization, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, regulation of DNA metabolic process, positive regulation of DNA metabolic process, regulation of DNA ligation, positive regulation of DNA ligation, positive regulation of nitrogen compound metabolic process,protein oligomerization, protein homooligomerization, meiotic cell cycle, M phase of meiotic cell cycle, macromolecular complex assembly, protein complex biogenesis,
相关产品： YT3965,YT3964,YP1106,YP0376,KA4261C,KA1506C
细胞定位： Nucleus . Cytoplasm . Cytoplasm, perinuclear region. Mitochondrion matrix . Chromosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Colocalizes with RAD51AP1 and RPA2 to multiple nuclear foci upon induction of DNA damage (PubMed:20154705). DNA damage induces an increase in nuclear levels (PubMed:20154705). Together with FIGNL1, redistributed in discrete nuclear DNA damage-induced foci after ionizing radiation (IR) or camptothecin (CPT) treatment (PubMed:23754376). Accumulated at sites of DNA damage in a SPIDR-dependent manner (PubMed:23509288). Recruited at sites of DNA damage in a MCM9-MCM8-dependent manner (PubMed:23401855). Colocalizes with ERCC5/XPG to nuclear foci in S phase (PubMed:26833090). .
组织表达： Highly expressed in testis and thymus, followed by small intestine, placenta, colon, pancreas and ovary. Weakly expressed in breast.
其他名称： DNA repair protein RAD51 homolog 1 (HsRAD51) (hRAD51) (RAD51 homolog A)
功能： M phase, double-strand break repair via homologous recombination, recombinational repair, DNA metabolic process,DNA replication, DNA-dependent DNA replication, DNA unwinding during replication, DNA repair, double-strand break repair, DNA recombination, mitotic recombination, protein complex assembly, response to DNA damage stimulus, cell cycle, meiosis, meiosis I, reciprocal meiotic recombination, positive regulation of macromolecule metabolic process, cell cycle process, cell cycle phase, DNA geometric change, DNA duplex unwinding, cellular response to stress,macromolecular complex subunit organization, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, regulation of DNA metabolic process, positive regulation of DNA metabolic process, regulation of DNA ligation, positive regulation of DNA ligation, positive regulation of nitrogen compound metabolic process,protein oligomerization, protein homooligomerization, meiotic cell cycle, M phase of meiotic cell cycle, macromolecular complex assembly, protein complex biogenesis,
相关产品： YT3965,YT3964,YP1106,YP0376,KA4261C,KA1506C
细胞定位： Nucleus . Cytoplasm . Cytoplasm, perinuclear region. Mitochondrion matrix . Chromosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Colocalizes with RAD51AP1 and RPA2 to multiple nuclear foci upon induction of DNA damage (PubMed:20154705). DNA damage induces an increase in nuclear levels (PubMed:20154705). Together with FIGNL1, redistributed in discrete nuclear DNA damage-induced foci after ionizing radiation (IR) or camptothecin (CPT) treatment (PubMed:23754376). Accumulated at sites of DNA damage in a SPIDR-dependent manner (PubMed:23509288). Recruited at sites of DNA damage in a MCM9-MCM8-dependent manner (PubMed:23401855). Colocalizes with ERCC5/XPG to nuclear foci in S phase (PubMed:26833090). .
组织表达： Highly expressed in testis and thymus, followed by small intestine, placenta, colon, pancreas and ovary. Weakly expressed in breast.
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