功能: intracellular protein transport, protein localization, negative regulation of cell proliferation, regulation of catabolic process, negative regulation of signal transduction, regulation of protein kinase cascade, negative regulation of cell communication, negative regulation of protein kinase cascade, protein transport, vesicle-mediated transport,endosome transport, cellular protein localization, regulation of cell proliferation, regulation of protein catabolic process, establishment of protein localization, regulation of JAK-STAT cascade, negative regulation of JAK-STAT cascade, intracellular transport, cellular macromolecule localization,
细胞定位: Cytoplasm . Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Endosome, multivesicular body membrane ; Peripheral membrane protein . Colocalizes with UBQLN1 in ubiquitin-rich cytoplasmic aggregates that are not endocytic compartments. .
组织表达: Ubiquitous expression in adult and fetal tissues with higher expression in testis and peripheral blood leukocytes.
功能: intracellular protein transport, protein localization, negative regulation of cell proliferation, regulation of catabolic process, negative regulation of signal transduction, regulation of protein kinase cascade, negative regulation of cell communication, negative regulation of protein kinase cascade, protein transport, vesicle-mediated transport,endosome transport, cellular protein localization, regulation of cell proliferation, regulation of protein catabolic process, establishment of protein localization, regulation of JAK-STAT cascade, negative regulation of JAK-STAT cascade, intracellular transport, cellular macromolecule localization,
细胞定位: Cytoplasm . Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Endosome, multivesicular body membrane ; Peripheral membrane protein . Colocalizes with UBQLN1 in ubiquitin-rich cytoplasmic aggregates that are not endocytic compartments. .
组织表达: Ubiquitous expression in adult and fetal tissues with higher expression in testis and peripheral blood leukocytes.