其他名称： Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Insulin receptor-binding protein Grb-IR)
功能： cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, cell-cell signaling, insulin receptor signaling pathway, response to endogenous stimulus, response to hormone stimulus, negative regulation of signal transduction, response to organic substance, negative regulation of cell communication, regulation of glucose transport, negative regulation of glucose transport, response to insulin stimulus, cellular response to insulin stimulus, cellular response to hormone stimulus,response to peptide hormone stimulus, regulation of glucose import, negative regulation of glucose import, regulation of insulin receptor signaling pathway, negative regulation of insulin receptor signaling pathway, insulin-like growth factor receptor signaling pathway, negative regulation of response to stimulus, negative regulation of transport,
相关产品： YT2054,YP0557,KA4109C,KA1485C
细胞定位： Cytoplasm . When complexed with NEDD4 and IGF1R, follows IGF1R internalization, remaining associated with early endosomes. Uncouples from IGF1R-containing endosomes before the sorting of the receptor to the lysosomal compartment (By similarity). .
组织表达： Widely expressed in fetal and adult tissues, including fetal and postnatal liver, lung, kidney, skeletal muscle, heart, spleen, skin and brain.
其他名称： Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Insulin receptor-binding protein Grb-IR)
功能： cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, cell-cell signaling, insulin receptor signaling pathway, response to endogenous stimulus, response to hormone stimulus, negative regulation of signal transduction, response to organic substance, negative regulation of cell communication, regulation of glucose transport, negative regulation of glucose transport, response to insulin stimulus, cellular response to insulin stimulus, cellular response to hormone stimulus,response to peptide hormone stimulus, regulation of glucose import, negative regulation of glucose import, regulation of insulin receptor signaling pathway, negative regulation of insulin receptor signaling pathway, insulin-like growth factor receptor signaling pathway, negative regulation of response to stimulus, negative regulation of transport,
相关产品： YT2054,YP0557,KA4109C,KA1485C
细胞定位： Cytoplasm . When complexed with NEDD4 and IGF1R, follows IGF1R internalization, remaining associated with early endosomes. Uncouples from IGF1R-containing endosomes before the sorting of the receptor to the lysosomal compartment (By similarity). .
组织表达： Widely expressed in fetal and adult tissues, including fetal and postnatal liver, lung, kidney, skeletal muscle, heart, spleen, skin and brain.
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