功能： MAPKKK cascade, activation of MAPK activity, cell morphogenesis, cell morphogenesis involved in differentiation,angiogenesis, blood vessel development, patterning of blood vessels, response to hypoxia, ameboidal cell migration,morphogenesis of a branching structure, neuron migration, cell activation, vasculature development, reproductive developmental process, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cellular ion homeostasis, cellular calcium ion homeostasis, cellular metal ion homeostasis, apoptosis, cell motion, chemotaxis, defense response, inflammatory response, immune response, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, elevation of cytosolic calcium ion concentration,intracellular signaling cascade, protein kinase cascade, gamete generation, germ cell development, pattern specification process, axonogenesis, axon guidance, behavior, locomotory behavior, motor axon guidance, cell death,cell proliferation, germ cell migration, response to wounding, response to virus, programmed cell death, viral reproduction, death, phosphorylation, cell migration, viral infectious cycle, initiation of viral infection, regulation of phosphate metabolic process, cellular homeostasis, sexual reproduction, viral reproductive process, cellular cation homeostasis, cellular di-, tri-valent inorganic cation homeostasis, cell projection organization, neuron differentiation,regulation of cell migration, neuron projection development, multicellular organism reproduction, mononuclear cell proliferation, cellular component morphogenesis, cell part morphogenesis, positive regulation of kinase activity, tube morphogenesis, tube development, regulation of locomotion, T cell proliferation, T cell activation, regulation of phosphorylation, taxis, homeostatic process, positive regulation of catalytic activity, regulation of MAP kinase activity,positive regulation of MAP kinase activity, regulation of kinase activity, positive regulation of molecular function,leukocyte activation, regulation of protein kinase activity, positive regulation of protein kinase activity, lymphocyte activation, lymphocyte proliferation, blood vessel morphogenesis, reproductive process in a multicellular organism,reproductive cellular process, neuron development, cell morphogenesis involved in neuron differentiation, branching morphogenesis of a tube, neuron projection morphogenesis, cell projection morphogenesis, cell motility, chemical homeostasis, ion homeostasis, regulation of phosphorus metabolic process, regulation of cell motion, regulation of transferase activity, positive regulation of transferase activity, cytosolic calcium ion homeostasis, localization of cell,metal ion homeostasis, di-, tri-valent inorganic cation homeostasis, calcium ion homeostasis, cation homeostasis,cellular chemical homeostasis, response to oxygen levels, leukocyte proliferation,
相关产品： YT1800,YP0917,YM3546,KA4384C,KA1441C
细胞定位： Cell membrane ; Multi-pass membrane protein . Cell junction. Early endosome. Late endosome. Lysosome. In unstimulated cells, diffuse pattern on plasma membrane. On agonist stimulation, colocalizes with ITCH at the plasma membrane where it becomes ubiquitinated. In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation cluster (SMAC).
组织表达： Expressed in numerous tissues, such as peripheral blood leukocytes, spleen, thymus, spinal cord, heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, cerebellum, cerebral cortex and medulla (in microglia as well as in astrocytes), brain microvascular, coronary artery and umbilical cord endothelial cells. Isoform 1 is predominant in all tissues tested.
功能： MAPKKK cascade, activation of MAPK activity, cell morphogenesis, cell morphogenesis involved in differentiation,angiogenesis, blood vessel development, patterning of blood vessels, response to hypoxia, ameboidal cell migration,morphogenesis of a branching structure, neuron migration, cell activation, vasculature development, reproductive developmental process, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cellular ion homeostasis, cellular calcium ion homeostasis, cellular metal ion homeostasis, apoptosis, cell motion, chemotaxis, defense response, inflammatory response, immune response, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, elevation of cytosolic calcium ion concentration,intracellular signaling cascade, protein kinase cascade, gamete generation, germ cell development, pattern specification process, axonogenesis, axon guidance, behavior, locomotory behavior, motor axon guidance, cell death,cell proliferation, germ cell migration, response to wounding, response to virus, programmed cell death, viral reproduction, death, phosphorylation, cell migration, viral infectious cycle, initiation of viral infection, regulation of phosphate metabolic process, cellular homeostasis, sexual reproduction, viral reproductive process, cellular cation homeostasis, cellular di-, tri-valent inorganic cation homeostasis, cell projection organization, neuron differentiation,regulation of cell migration, neuron projection development, multicellular organism reproduction, mononuclear cell proliferation, cellular component morphogenesis, cell part morphogenesis, positive regulation of kinase activity, tube morphogenesis, tube development, regulation of locomotion, T cell proliferation, T cell activation, regulation of phosphorylation, taxis, homeostatic process, positive regulation of catalytic activity, regulation of MAP kinase activity,positive regulation of MAP kinase activity, regulation of kinase activity, positive regulation of molecular function,leukocyte activation, regulation of protein kinase activity, positive regulation of protein kinase activity, lymphocyte activation, lymphocyte proliferation, blood vessel morphogenesis, reproductive process in a multicellular organism,reproductive cellular process, neuron development, cell morphogenesis involved in neuron differentiation, branching morphogenesis of a tube, neuron projection morphogenesis, cell projection morphogenesis, cell motility, chemical homeostasis, ion homeostasis, regulation of phosphorus metabolic process, regulation of cell motion, regulation of transferase activity, positive regulation of transferase activity, cytosolic calcium ion homeostasis, localization of cell,metal ion homeostasis, di-, tri-valent inorganic cation homeostasis, calcium ion homeostasis, cation homeostasis,cellular chemical homeostasis, response to oxygen levels, leukocyte proliferation,
相关产品： YT1800,YP0917,YM3546,KA4384C,KA1441C
细胞定位： Cell membrane ; Multi-pass membrane protein . Cell junction. Early endosome. Late endosome. Lysosome. In unstimulated cells, diffuse pattern on plasma membrane. On agonist stimulation, colocalizes with ITCH at the plasma membrane where it becomes ubiquitinated. In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation cluster (SMAC).
组织表达： Expressed in numerous tissues, such as peripheral blood leukocytes, spleen, thymus, spinal cord, heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, cerebellum, cerebral cortex and medulla (in microglia as well as in astrocytes), brain microvascular, coronary artery and umbilical cord endothelial cells. Isoform 1 is predominant in all tissues tested.
在线咨询
湘公网安备