Phospho Survivin (T34) Cell-Based Colorimetric ELISA Kit

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商品货号： PLA000339

￥600元

规格：

40μL 100μL 200μL

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说明书

商品描述

发货日期： 14
基因名称： BIRC5
Human_gene_id： 332
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=332
Human_swiss_prot_no： O15392
Human_swiss_link： http://www.uniprot.org/uniprotkb/O15392/entry
Mouse_swiss_prot_no： O70201
Mouse_swiss_link： http://www.uniprot.org/uniprot/O70201
Rat_swiss_prot_no： Q9JHY7
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941Q9JHY7
储存： 2-8°C/6 months
说明书： KA1337C.pdf
其他名称： Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor 4) (Apoptosis inhibitor survivin)
功能： cell cycle checkpoint, G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, mitotic cell cycle, M phase,nuclear division, cytokinesis, apoptosis, anti-apoptosis, cell cycle, chromosome segregation, mitosis, regulation of exit from mitosis, regulation of mitotic cell cycle, cell death, negative regulation of peptidase activity, regulation of cell cycle process, regulation of cell death, programmed cell death, death, cell cycle process, cell cycle phase, protein complex localization, positive regulation of exit from mitosis, spindle checkpoint, regulation of apoptosis, negative regulation of apoptosis, regulation of programmed cell death, negative regulation of programmed cell death, negative regulation of catalytic activity, negative regulation of caspase activity, regulation of caspase activity, negative regulation of molecular function, positive regulation of cell cycle, positive regulation of mitotic cell cycle, organelle fission,chromosome localization, cell division, establishment of chromosome localization, interphase, interphase of mitotic cell cycle, regulation of hydrolase activity, negative regulation of hydrolase activity, organelle localization, establishment of organelle localization, regulation of cell cycle, regulation of peptidase activity, regulation of endopeptidase activity,negative regulation of cell death,
相关产品： YT4473,YT4472,YP1132,YP0319,YM3419,YM3386,KA4296C,KA1337C
细胞定位： Cytoplasm . Nucleus . Chromosome . Chromosome, centromere . Cytoplasm, cytoskeleton, spindle . Chromosome, centromere, kinetochore . Midbody . Localizes at the centromeres from prophase to metaphase, at the spindle midzone during anaphase and a the midbody during telophase and cytokinesis. Accumulates in the nucleus upon treatment with leptomycin B (LMB), a XPO1/CRM1 nuclear export inhibitor (By similarity). Localizes on chromosome arms and inner centromeres from prophase through metaphase. Localizes to kinetochores in metaphase, distributes to the midzone microtubules in anaphase and at telophase, localizes exclusively to the midbody (PubMed:11084331). Colocalizes with AURKB at mitotic chromosomes (PubMed:14610074). Acetylation at Lys-129 directs its localization to the nucleus by enhancing homodimerization and thereby inhibiting XPO1/CRM1-mediated nuclear export (PubMed:20826784). .
组织表达： Expressed only in fetal kidney and liver, and to lesser extent, lung and brain (PubMed:10626797). Abundantly expressed in adenocarcinoma (lung, pancreas, colon, breast, and prostate) and in high-grade lymphomas (PubMed:14741722, PubMed:16329164). Also expressed in various renal cell carcinoma cell lines (PubMed:10626797). Expressed in cochlea including the organ of Corti, the lateral wall, the interdental cells of the Limbus as well as in Schwann cells and cells of the cochlear nerve and the spiral ganglions (at protein level). Not expressed in cells of the inner and outer sulcus or the Reissner's membrane (at protein level) (PubMed:21364656, PubMed:20627126).
科研货号： PLA000339

Phospho Survivin (T34) Cell-Based Colorimetric ELISA Kit

Catalog No PLA000339

Product information

发货日期： 14
基因名称： BIRC5
Human_gene_id： 332
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=332
Human_swiss_prot_no： O15392
Human_swiss_link： http://www.uniprot.org/uniprotkb/O15392/entry
Mouse_swiss_prot_no： O70201
Mouse_swiss_link： http://www.uniprot.org/uniprot/O70201
Rat_swiss_prot_no： Q9JHY7
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941Q9JHY7
储存： 2-8°C/6 months
说明书： KA1337C.pdf
其他名称： Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor 4) (Apoptosis inhibitor survivin)
功能： cell cycle checkpoint, G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, mitotic cell cycle, M phase,nuclear division, cytokinesis, apoptosis, anti-apoptosis, cell cycle, chromosome segregation, mitosis, regulation of exit from mitosis, regulation of mitotic cell cycle, cell death, negative regulation of peptidase activity, regulation of cell cycle process, regulation of cell death, programmed cell death, death, cell cycle process, cell cycle phase, protein complex localization, positive regulation of exit from mitosis, spindle checkpoint, regulation of apoptosis, negative regulation of apoptosis, regulation of programmed cell death, negative regulation of programmed cell death, negative regulation of catalytic activity, negative regulation of caspase activity, regulation of caspase activity, negative regulation of molecular function, positive regulation of cell cycle, positive regulation of mitotic cell cycle, organelle fission,chromosome localization, cell division, establishment of chromosome localization, interphase, interphase of mitotic cell cycle, regulation of hydrolase activity, negative regulation of hydrolase activity, organelle localization, establishment of organelle localization, regulation of cell cycle, regulation of peptidase activity, regulation of endopeptidase activity,negative regulation of cell death,
相关产品： YT4473,YT4472,YP1132,YP0319,YM3419,YM3386,KA4296C,KA1337C
细胞定位： Cytoplasm . Nucleus . Chromosome . Chromosome, centromere . Cytoplasm, cytoskeleton, spindle . Chromosome, centromere, kinetochore . Midbody . Localizes at the centromeres from prophase to metaphase, at the spindle midzone during anaphase and a the midbody during telophase and cytokinesis. Accumulates in the nucleus upon treatment with leptomycin B (LMB), a XPO1/CRM1 nuclear export inhibitor (By similarity). Localizes on chromosome arms and inner centromeres from prophase through metaphase. Localizes to kinetochores in metaphase, distributes to the midzone microtubules in anaphase and at telophase, localizes exclusively to the midbody (PubMed:11084331). Colocalizes with AURKB at mitotic chromosomes (PubMed:14610074). Acetylation at Lys-129 directs its localization to the nucleus by enhancing homodimerization and thereby inhibiting XPO1/CRM1-mediated nuclear export (PubMed:20826784). .
组织表达： Expressed only in fetal kidney and liver, and to lesser extent, lung and brain (PubMed:10626797). Abundantly expressed in adenocarcinoma (lung, pancreas, colon, breast, and prostate) and in high-grade lymphomas (PubMed:14741722, PubMed:16329164). Also expressed in various renal cell carcinoma cell lines (PubMed:10626797). Expressed in cochlea including the organ of Corti, the lateral wall, the interdental cells of the Limbus as well as in Schwann cells and cells of the cochlear nerve and the spiral ganglions (at protein level). Not expressed in cells of the inner and outer sulcus or the Reissner's membrane (at protein level) (PubMed:21364656, PubMed:20627126).
科研货号： PLA000339

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