其他名称： Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
功能： MAPKKK cascade, inactivation of MAPK activity, regulation of cell growth, regulation of protein amino acid phosphorylation, negative regulation of protein amino acid phosphorylation, regulation of DNA replication, RNA processing, negative regulation of protein kinase activity, protein amino acid dephosphorylation, membrane lipid metabolic process, sphingolipid metabolic process, ceramide metabolic process, phosphorus metabolic process,phosphate metabolic process, induction of apoptosis, intracellular signaling cascade, protein kinase cascade,mesoderm development, regulation of cell size, RNA splicing, negative regulation of signal transduction, response to organic substance, negative regulation of phosphorus metabolic process, negative regulation of macromolecule metabolic process, regulation of protein kinase cascade, negative regulation of cell communication, negative regulation of protein kinase cascade, regulation of cell death, positive regulation of cell death, induction of programmed cell death, dephosphorylation, regulation of phosphate metabolic process, second-messenger-mediated signaling, regulation of Wnt receptor signaling pathway, regulation of cell adhesion, negative regulation of cell growth,regulation of protein modification process, negative regulation of protein modification process, regulation of cellular protein metabolic process, negative regulation of cellular protein metabolic process, regulation of cellular component size, negative regulation of kinase activity, regulation of growth, regulation of phosphorylation, negative regulation of phosphorylation, regulation of tyrosine phosphorylation of STAT protein, regulation of tyrosine phosphorylation of Stat3 protein, negative regulation of tyrosine phosphorylation of Stat3 protein, negative regulation of tyrosine phosphorylation of STAT protein, regulation of apoptosis, positive regulation of apoptosis, regulation of programmed cell death, positive regulation of programmed cell death, negative regulation of catalytic activity, regulation of MAP kinase activity, negative regulation of MAP kinase activity, regulation of kinase activity, negative regulation of molecular function, regulation of transcription, negative regulation of cell size, regulation of protein kinase activity,negative regulation of growth, negative regulation of phosphate metabolic process, regulation of JAK-STAT cascade,negative regulation of JAK-STAT cascade, sphingoid metabolic process, regulation of peptidyl-tyrosine phosphorylation,negative regulation of peptidyl-tyrosine phosphorylation, regulation of DNA metabolic process, regulation of phosphorus metabolic process, negative regulation of protein metabolic process, regulation of transferase activity,negative regulation of transferase activity,
相关产品： YT3830,YP0889,YN3043,KA4251C,KA1325C
细胞定位： Cytoplasm . Nucleus . Chromosome, centromere . Cytoplasm, cytoskeleton, spindle pole . In prometaphase cells, but not in anaphase cells, localizes at centromeres (PubMed:16541025). During mitosis, also found at spindle poles (PubMed:16541025). Centromeric localization requires the presence of SGO2 (By similarity). .
其他名称： Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
功能： MAPKKK cascade, inactivation of MAPK activity, regulation of cell growth, regulation of protein amino acid phosphorylation, negative regulation of protein amino acid phosphorylation, regulation of DNA replication, RNA processing, negative regulation of protein kinase activity, protein amino acid dephosphorylation, membrane lipid metabolic process, sphingolipid metabolic process, ceramide metabolic process, phosphorus metabolic process,phosphate metabolic process, induction of apoptosis, intracellular signaling cascade, protein kinase cascade,mesoderm development, regulation of cell size, RNA splicing, negative regulation of signal transduction, response to organic substance, negative regulation of phosphorus metabolic process, negative regulation of macromolecule metabolic process, regulation of protein kinase cascade, negative regulation of cell communication, negative regulation of protein kinase cascade, regulation of cell death, positive regulation of cell death, induction of programmed cell death, dephosphorylation, regulation of phosphate metabolic process, second-messenger-mediated signaling, regulation of Wnt receptor signaling pathway, regulation of cell adhesion, negative regulation of cell growth,regulation of protein modification process, negative regulation of protein modification process, regulation of cellular protein metabolic process, negative regulation of cellular protein metabolic process, regulation of cellular component size, negative regulation of kinase activity, regulation of growth, regulation of phosphorylation, negative regulation of phosphorylation, regulation of tyrosine phosphorylation of STAT protein, regulation of tyrosine phosphorylation of Stat3 protein, negative regulation of tyrosine phosphorylation of Stat3 protein, negative regulation of tyrosine phosphorylation of STAT protein, regulation of apoptosis, positive regulation of apoptosis, regulation of programmed cell death, positive regulation of programmed cell death, negative regulation of catalytic activity, regulation of MAP kinase activity, negative regulation of MAP kinase activity, regulation of kinase activity, negative regulation of molecular function, regulation of transcription, negative regulation of cell size, regulation of protein kinase activity,negative regulation of growth, negative regulation of phosphate metabolic process, regulation of JAK-STAT cascade,negative regulation of JAK-STAT cascade, sphingoid metabolic process, regulation of peptidyl-tyrosine phosphorylation,negative regulation of peptidyl-tyrosine phosphorylation, regulation of DNA metabolic process, regulation of phosphorus metabolic process, negative regulation of protein metabolic process, regulation of transferase activity,negative regulation of transferase activity,
相关产品： YT3830,YP0889,YN3043,KA4251C,KA1325C
细胞定位： Cytoplasm . Nucleus . Chromosome, centromere . Cytoplasm, cytoskeleton, spindle pole . In prometaphase cells, but not in anaphase cells, localizes at centromeres (PubMed:16541025). During mitosis, also found at spindle poles (PubMed:16541025). Centromeric localization requires the presence of SGO2 (By similarity). .
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