其他名称: Death domain-associated protein 6 (Daxx) (hDaxx) (ETS1-associated protein 1) (EAP1) (Fas death domain-associated protein)
功能: MAPKKK cascade, activation of MAPK activity, cytokinesis after mitosis, cytokinesis, regulation of protein amino acid phosphorylation, transcription, regulation of transcription, DNA-dependent, protein amino acid phosphorylation,phosphorus metabolic process, phosphate metabolic process, apoptosis, induction of apoptosis, cell cycle, intracellular signaling cascade, protein kinase cascade, JNK cascade, activation of JUN kinase activity, cell death, induction of apoptosis by extracellular signals, negative regulation of biosynthetic process, negative regulation of macromolecule biosynthetic process, negative regulation of macromolecule metabolic process, regulation of protein kinase cascade,negative regulation of gene expression, regulation of cell death, positive regulation of cell death, programmed cell death, induction of programmed cell death, death, phosphorylation, negative regulation of transcription, regulation of phosphate metabolic process, cell cycle process, steroid hormone receptor signaling pathway, androgen receptor signaling pathway, intracellular receptor-mediated signaling pathway, stress-activated protein kinase signaling pathway, negative regulation of cellular biosynthetic process, regulation of protein modification process, regulation of cellular protein metabolic process, cytokinesis during cell cycle, cellular response to stress, positive regulation of kinase activity, regulation of phosphorylation, regulation of apoptosis, positive regulation of apoptosis, regulation of programmed cell death, positive regulation of programmed cell death, positive regulation of catalytic activity,regulation of MAP kinase activity, positive regulation of MAP kinase activity, regulation of MAPKKK cascade, regulation of JUN kinase activity, positive regulation of JUN kinase activity, regulation of kinase activity, positive regulation of molecular function, regulation of transcription, regulation of protein kinase activity, positive regulation of protein kinase activity, negative regulation of transcription, DNA-dependent, negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, regulation of JNK cascade, negative regulation of nitrogen compound metabolic process, regulation of phosphorus metabolic process, regulation of RNA metabolic process, negative regulation of RNA metabolic process, cell division, regulation of transferase activity, positive regulation of transferase activity, regulation of stress-activated protein kinase signaling pathway, regulation of cellular response to stress,
相关产品: YT1293,YT1292,YP0625,KA4072C,KA1244C
细胞定位: Cytoplasm . Nucleus, nucleoplasm . Nucleus, PML body . Nucleus, nucleolus . Chromosome, centromere . Dispersed throughout the nucleoplasm, in PML/POD/ND10 nuclear bodies, and in nucleoli (Probable). Colocalizes with histone H3.3, ATRX, HIRA and ASF1A at PML-nuclear bodies (PubMed:12953102, PubMed:14990586, PubMed:23222847, PubMed:24200965). Colocalizes with a subset of interphase centromeres, but is absent from mitotic centromeres (PubMed:9645950). Detected in cytoplasmic punctate structures (PubMed:11842083). Translocates from the nucleus to the cytoplasm upon glucose deprivation or oxidative stress (PubMed:12968034). Colocalizes with RASSF1 in the nucleus (PubMed:18566590). Colocalizes with USP7 in nucleoplasma with accumulation in speckled structures (PubMed:16845383). .; [Isoform beta]: Nucleus . Diffuse nuclear distribution pattern and no comparable dot-like accumulation of isoform 1. .; [Isoform gamma]: Nucleus . Diffuse nuclear distribution pattern and no comparable dot-like accumulation of isoform 1. .
其他名称: Death domain-associated protein 6 (Daxx) (hDaxx) (ETS1-associated protein 1) (EAP1) (Fas death domain-associated protein)
功能: MAPKKK cascade, activation of MAPK activity, cytokinesis after mitosis, cytokinesis, regulation of protein amino acid phosphorylation, transcription, regulation of transcription, DNA-dependent, protein amino acid phosphorylation,phosphorus metabolic process, phosphate metabolic process, apoptosis, induction of apoptosis, cell cycle, intracellular signaling cascade, protein kinase cascade, JNK cascade, activation of JUN kinase activity, cell death, induction of apoptosis by extracellular signals, negative regulation of biosynthetic process, negative regulation of macromolecule biosynthetic process, negative regulation of macromolecule metabolic process, regulation of protein kinase cascade,negative regulation of gene expression, regulation of cell death, positive regulation of cell death, programmed cell death, induction of programmed cell death, death, phosphorylation, negative regulation of transcription, regulation of phosphate metabolic process, cell cycle process, steroid hormone receptor signaling pathway, androgen receptor signaling pathway, intracellular receptor-mediated signaling pathway, stress-activated protein kinase signaling pathway, negative regulation of cellular biosynthetic process, regulation of protein modification process, regulation of cellular protein metabolic process, cytokinesis during cell cycle, cellular response to stress, positive regulation of kinase activity, regulation of phosphorylation, regulation of apoptosis, positive regulation of apoptosis, regulation of programmed cell death, positive regulation of programmed cell death, positive regulation of catalytic activity,regulation of MAP kinase activity, positive regulation of MAP kinase activity, regulation of MAPKKK cascade, regulation of JUN kinase activity, positive regulation of JUN kinase activity, regulation of kinase activity, positive regulation of molecular function, regulation of transcription, regulation of protein kinase activity, positive regulation of protein kinase activity, negative regulation of transcription, DNA-dependent, negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, regulation of JNK cascade, negative regulation of nitrogen compound metabolic process, regulation of phosphorus metabolic process, regulation of RNA metabolic process, negative regulation of RNA metabolic process, cell division, regulation of transferase activity, positive regulation of transferase activity, regulation of stress-activated protein kinase signaling pathway, regulation of cellular response to stress,
相关产品: YT1293,YT1292,YP0625,KA4072C,KA1244C
细胞定位: Cytoplasm . Nucleus, nucleoplasm . Nucleus, PML body . Nucleus, nucleolus . Chromosome, centromere . Dispersed throughout the nucleoplasm, in PML/POD/ND10 nuclear bodies, and in nucleoli (Probable). Colocalizes with histone H3.3, ATRX, HIRA and ASF1A at PML-nuclear bodies (PubMed:12953102, PubMed:14990586, PubMed:23222847, PubMed:24200965). Colocalizes with a subset of interphase centromeres, but is absent from mitotic centromeres (PubMed:9645950). Detected in cytoplasmic punctate structures (PubMed:11842083). Translocates from the nucleus to the cytoplasm upon glucose deprivation or oxidative stress (PubMed:12968034). Colocalizes with RASSF1 in the nucleus (PubMed:18566590). Colocalizes with USP7 in nucleoplasma with accumulation in speckled structures (PubMed:16845383). .; [Isoform beta]: Nucleus . Diffuse nuclear distribution pattern and no comparable dot-like accumulation of isoform 1. .; [Isoform gamma]: Nucleus . Diffuse nuclear distribution pattern and no comparable dot-like accumulation of isoform 1. .