其他名称： Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog)
功能： cell cycle checkpoint, DNA replication checkpoint, DNA damage checkpoint, DNA metabolic process, DNA replication,regulation of DNA replication, DNA repair, response to DNA damage stimulus, cell cycle, mitotic cell cycle checkpoint,intracellular signaling cascade, regulation of mitotic cell cycle, negative regulation of DNA replication, negative regulation of biosynthetic process, negative regulation of macromolecule biosynthetic process, negative regulation of macromolecule metabolic process, regulation of phosphate metabolic process, regulation of DNA replication initiation,negative regulation of cellular biosynthetic process, DNA integrity checkpoint, negative regulation of DNA replication initiation, cellular response to stress, regulation of phosphorylation, DNA damage response, signal transduction,negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, regulation of DNA metabolic process, negative regulation of DNA metabolic process, negative regulation of nitrogen compound metabolic process, regulation of phosphorus metabolic process, regulation of cell cycle,
相关产品： YT3958,YT3957,YP1203,YP0291,KA4260C,KA1219C
细胞定位： Nucleus . Phosphorylated form redistributes to discrete nuclear foci upon DNA damage.
组织表达： Overexpressed in various cancer cell lines and in colon carcinoma (at protein level). Isoform 2 and isoform 3 are the most abundant isoforms in non irradiated cells (at protein level). Ubiquitous at low levels. Highly expressed in testis, where it is expressed within the germinal epithelium of the seminiferous tubuli. Weakly expressed in seminomas (testicular tumors).
其他名称： Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog)
功能： cell cycle checkpoint, DNA replication checkpoint, DNA damage checkpoint, DNA metabolic process, DNA replication,regulation of DNA replication, DNA repair, response to DNA damage stimulus, cell cycle, mitotic cell cycle checkpoint,intracellular signaling cascade, regulation of mitotic cell cycle, negative regulation of DNA replication, negative regulation of biosynthetic process, negative regulation of macromolecule biosynthetic process, negative regulation of macromolecule metabolic process, regulation of phosphate metabolic process, regulation of DNA replication initiation,negative regulation of cellular biosynthetic process, DNA integrity checkpoint, negative regulation of DNA replication initiation, cellular response to stress, regulation of phosphorylation, DNA damage response, signal transduction,negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, regulation of DNA metabolic process, negative regulation of DNA metabolic process, negative regulation of nitrogen compound metabolic process, regulation of phosphorus metabolic process, regulation of cell cycle,
相关产品： YT3958,YT3957,YP1203,YP0291,KA4260C,KA1219C
细胞定位： Nucleus . Phosphorylated form redistributes to discrete nuclear foci upon DNA damage.
组织表达： Overexpressed in various cancer cell lines and in colon carcinoma (at protein level). Isoform 2 and isoform 3 are the most abundant isoforms in non irradiated cells (at protein level). Ubiquitous at low levels. Highly expressed in testis, where it is expressed within the germinal epithelium of the seminiferous tubuli. Weakly expressed in seminomas (testicular tumors).
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