功能： skeletal system development, ossification, eye development, in utero embryonic development, blastocyst development, blastocyst formation, trophectodermal cell differentiation, liver development, placenta development,embryonic placenta development, immune system development, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, global, sensory organ development, female pregnancy, embryonic development ending in birth or egg hatching, positive regulation of biosynthetic process, positive regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, positive regulation of gene expression, hemopoiesis,myeloid cell differentiation, erythrocyte differentiation, megakaryocyte differentiation, respiratory tube development,lung development, embryonic camera-type eye development, positive regulation of cellular biosynthetic process,multicellular organism reproduction, erythrocyte homeostasis, tube development, homeostatic process, chordate embryonic development, camera-type eye development, enucleate erythrocyte differentiation, regulation of transcription, positive regulation of transcription from RNA polymerase II promoter, global, positive regulation of transcription, DNA-dependent, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of transcription, positive regulation of transcription from RNA polymerase II promoter,embryonic eye morphogenesis, hemopoietic or lymphoid organ development, embryonic organ morphogenesis,embryonic organ development, eye morphogenesis, camera-type eye morphogenesis, embryonic camera-type eye morphogenesis, embryonic morphogenesis, reproductive process in a multicellular organism, embryonic skeletal system development, homeostasis of number of cells, positive regulation of nitrogen compound metabolic process,regulation of RNA metabolic process, positive regulation of RNA metabolic process, embryonic process involved in female pregnancy, definitive hemopoiesis, bone development, respiratory system development,
细胞定位： Nucleus. Cytoplasm. Nuclear location is governed by glycosylated/phosphorylated states. Insulin promotes nuclear location, while glucagon favors cytoplasmic location.
组织表达： Up-regulated in adenocarcinomas of the stomach (at protein level). Isoform 3 is ubiquitously expressed at low levels.
功能： skeletal system development, ossification, eye development, in utero embryonic development, blastocyst development, blastocyst formation, trophectodermal cell differentiation, liver development, placenta development,embryonic placenta development, immune system development, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, global, sensory organ development, female pregnancy, embryonic development ending in birth or egg hatching, positive regulation of biosynthetic process, positive regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, positive regulation of gene expression, hemopoiesis,myeloid cell differentiation, erythrocyte differentiation, megakaryocyte differentiation, respiratory tube development,lung development, embryonic camera-type eye development, positive regulation of cellular biosynthetic process,multicellular organism reproduction, erythrocyte homeostasis, tube development, homeostatic process, chordate embryonic development, camera-type eye development, enucleate erythrocyte differentiation, regulation of transcription, positive regulation of transcription from RNA polymerase II promoter, global, positive regulation of transcription, DNA-dependent, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of transcription, positive regulation of transcription from RNA polymerase II promoter,embryonic eye morphogenesis, hemopoietic or lymphoid organ development, embryonic organ morphogenesis,embryonic organ development, eye morphogenesis, camera-type eye morphogenesis, embryonic camera-type eye morphogenesis, embryonic morphogenesis, reproductive process in a multicellular organism, embryonic skeletal system development, homeostasis of number of cells, positive regulation of nitrogen compound metabolic process,regulation of RNA metabolic process, positive regulation of RNA metabolic process, embryonic process involved in female pregnancy, definitive hemopoiesis, bone development, respiratory system development,
细胞定位： Nucleus. Cytoplasm. Nuclear location is governed by glycosylated/phosphorylated states. Insulin promotes nuclear location, while glucagon favors cytoplasmic location.
组织表达： Up-regulated in adenocarcinomas of the stomach (at protein level). Isoform 3 is ubiquitously expressed at low levels.
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